Results 31 to 40 of about 21,718 (291)

The role of IgE-receptors in IgE-dependent airway smooth muscle cell remodelling. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: In allergic asthma, IgE increases airway remodelling but the mechanism is incompletely understood. Airway remodelling consists of two independent events increased cell numbers and enhanced extracellular matrix deposition, and the mechanism by
Michael Roth   +5 more
doaj   +1 more source

Collagen mRNA levels changes during colorectal cancer carcinogenesis

open access: yesBMC Cancer, 2009
Background Invasive growth of epithelial cancers is a complex multi-step process which involves dissolution of the basement membrane. Type IV collagen is a major component in most basement membranes.
Tveit Kjell M   +5 more
doaj   +1 more source

Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors

open access: yesMolecular Therapy: Methods & Clinical Development, 2022
Recessive dystrophic epidermolysis bullosa, a devastating skin fragility disease characterized by recurrent skin blistering, scarring, and a high risk of developing squamous cell carcinoma is caused by mutations in COL7A1, the gene encoding type VII ...
Marta García   +12 more
doaj   +1 more source

Sources of Collagen for Biomaterials in Skin Wound Healing

open access: yesBioengineering, 2019
Collagen is the most frequently used protein in the fields of biomaterials and regenerative medicine. Within the skin, collagen type I and III are the most abundant, while collagen type VII is associated with pathologies of the dermal−epidermal ...
Evan Davison-Kotler   +2 more
doaj   +1 more source

Adjuvant polyarthritis. vii. The role of type ii collagen in pathogenesis [PDF]

open access: yesArthritis & Rheumatism, 1982
AbstractThe development of immune response in rats directed toward EL4 cells, after the injection of EL4 cells suspended in a saline/oil emulsion, was enhanced by the incorporation of Mycobacterium into the saline/oil emulsion; the incorporation of type II collagen into the saline–acetic acid/oil emulsion in concentrations ranging from 0.5–25 μg/ml had
Y, Iizuka, Y H, Chang
openaire   +2 more sources

Type VII Collagen in the Human Accommodation System: Expression in Ciliary Body, Zonules, and Lens Capsule [PDF]

open access: yes, 2018
To investigate intraocular expression of COL7A1 and its protein product type VII collagen, particularly at the accommodation system. Eyes from 26 human adult donors were used.
Martin Schol   +13 more
core   +1 more source

Normal Molecular Weight of Type VII Collagen Produced by Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

open access: yes, 1993
Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abnormality in type VII collagen may be involved in the pathogenesis of this disorder.
O'Keefe, Edward   +3 more
core   +2 more sources

Cardiac valve disease: an unreported feature in Ehlers Danlos syndrome arthrocalasia type?

open access: yesItalian Journal of Pediatrics, 2012
Ehlers Danlos syndrome (EDS) athrocalasia type (type VII), is characterized by joint hypermobility, skin hyperextensibility and tissue fragility. No heart involvement has been reported. Two forms have been described: type VII A and VII B.
Melis Daniela   +6 more
doaj   +1 more source

Current approaches to the diagnosis of autoimmune bullous dermatoses

open access: yesVestnik Dermatologii i Venerologii, 2021
A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described.
Marianna B. Drozhdina   +2 more
doaj   +1 more source

Autoimmunity against type VII collagen in inflammatory bowel disease [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2009
Abstract Introduction The autoantigen: type VII collagen Autoimmunity to type VII collagen Inflammatory bowel disease Autoimmune phenomena in IBD Association of IBD with autoimmune diseases Autoimmunity to type VII collagen in IBD Autoimmunity against type VII collagen and EBA show a strong association with IBD Sequence of occurrence of skin ...
Hundorfean, Gheorghe   +2 more
openaire   +2 more sources

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