Results 31 to 40 of about 464,753 (192)

Mechanical properties of collagen fibrils [PDF]

open access: yes, 2007
The formation of collagen fibers from staggered subfibrils still lacks a universally accepted model. Determining the mechanical properties of single collagen fibrils ( diameter 50 - 200 nm) provides new insights into collagen structure. In this work, the
Bozec, L   +5 more
core   +1 more source

Native Autoantigen Complex Detects Pemphigoid Autoantibodies

open access: yesJID Innovations, 2023
Pemphigoid diseases are a group of autoimmune disorders characterized by subepidermal blistering in the skin and mucosa. Among them, mucous membrane pemphigoid (MMP) autoantibodies are characterized by targeting multiple molecules in the hemidesmosomes ...
Shoko Mai   +9 more
doaj   +1 more source

Increase in types IV and VI collagen in cherry haemangiomas [PDF]

open access: yes, 1992
The capillaries in cherry haemangiomas show perivascular hyalinized sheaths. In order to clarify the nature of this sheath material, the extracellular matrix of cherry haemangiomas from 20 normal volunteers (age range 30-64 years) was investigated using ...
Tamm, Ernst R.   +3 more
core   +1 more source

Passive transfer of collagen XVII-specific antibodies induces sustained blistering disease in adult mice

open access: yesOrphanet Journal of Rare Diseases, 2013
Background Bullous pemphigoid is a subepidermal blistering disorder associated with tissue-bound and circulating autoantibodies directed mainly to the hemidesmosomal component collagen XVII.
Chiriac Mircea Teodor   +11 more
doaj   +1 more source

Post-transcriptional mechanisms in type XVII collagen synthesis [PDF]

open access: yes, 2006
In chapter 1 we started with making an inventory of type XVII collagen directed research during the last three decades; on its role in normal healthy tissue and even more on its role in the pathogenesis in a range of diseases. We concluded that, although
Zalen, Sebastiaan van,   +1 more
openaire   +15 more sources

Effect of Low-Temperature Plasma Jet on Thermal Stability and Physical Structure of Type I Collagen [PDF]

open access: yes, 2012
This work is devoted to the characterization of type I collagen treated by a low-temperature plasma jet generated in ambient air to determine whether the resulting fibrous material is structurally preserved or reinforced.
Yousfi, Mohammed   +6 more
core   +1 more source

Development of an ELISA for sensitive and specific detection of IgA autoantibodies against BP180 in pemphigoid diseases

open access: yesOrphanet Journal of Rare Diseases, 2011
Background Pemphigoids are rare diseases associated with IgG, IgE and IgA autoantibodies against collagen XVII/BP180. An entity of the pemphigoid group is the lamina lucida-type of linear IgA disease (IgA pemphigoid) characterized by IgA autoantibodies ...
Kárpáti Sarolta   +9 more
doaj   +1 more source

C-terminal truncation impairs glycosylation of transmembrane collagen XVII and leads to intracellular accumulation [PDF]

open access: yes, 2006
Collagen XVII, a type II transmembrane protein in hemidesmosomes, is involved in the anchorage of stratified epithelia to the underlying mesenchyme. Its functions are regulated by ectodomain shedding, and its genetic defects lead to epidermal detachment ...
Franzke C. -W.   +6 more
core   +5 more sources

Immunohistochemical localization of collagen types I and VI in human skin wounds [PDF]

open access: yes, 1996
A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive ...
Penning, R.   +5 more
core   +1 more source

Collagen XVII Participates in Keratinocyte Adhesion to Collagen IV, and in p38MAPK-Dependent Migration and Cell Signaling [PDF]

open access: yesJournal of Investigative Dermatology, 2009
Collagen XVII (COL17) participates in keratinocyte adhesion and possibly migration, as COL17 defects disrupt keratinocyte-basal lamina adhesion and underlie the disease non-Herlitz junctional epidermolysis bullosa. Using small interference RNA (siRNA) to knock down COL17 expression in HaCaT cells, we assessed cell characteristics, including adhesion ...
Qiao, Hongjiang   +9 more
openaire   +5 more sources

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