Results 41 to 50 of about 300,263 (378)
Collagenase-Induced Mouse Model of Osteoarthritis—A Thorough Flow Cytometry Analysis
Life, 2022 Objectives: Osteoarthritis (OA) is a chronic degenerative disorder of the joint characterized by cartilage breakdown and synovial inflammation.
Blagovesta Boneva +4 more
doaj +1 more source
Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]
, 2003 To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim +5 more
core +1 more source
Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms. [PDF]
, 1994 Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an ...
Chandler DB +34 more
core +2 more sources
Endogenous Collagenases Regulate Osteoclast Fusion
Biomolecules, 2020 The precise regulation of osteoclast differentiation and function is crucial for the maintenance of healthy bone. Despite several reports of collagenase expression in bone tissues, the precise isoform expression as well as the role in osteoclasts are ...
Hyo Jeong Kim, Youngkyun Lee
doaj +1 more source
Indonesian Journal of Chemistry, 2023 Skin aging is associated with decreased skin firmness and excessive pigmentation, which is caused by the activity of aging enzymes. This process can be prevented with powerful antioxidants from nature, such as ferulic acid which is abundant in rice. This
Ernanin Dyah Wijayanti +3 more
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Human Platelet Collagenase [PDF]
Journal of Clinical Investigation, 1974 The presence of proteolytic enzymes such as cathepsin and elastase in platelets and the important role of collagen in platelet aggregation suggested that collagenase might be present in platelets. Epinephrine, ADP, and collagen liberate collagenase from platelets in plasma as measured by the hydrolysis of [(14)C]glycine-labeled collagen fibrils.
C M, Chesney, E, Harper, R W, Colman
openaire +2 more sources
Clinical, Cosmetic and Investigational Dermatology, 2015 Background In phytotherapy, the therapeutic potential is based on the combined action of different herbal drugs. Our objective was to evaluate the antioxidant, anti-collagenase (in vitro), and anti-wrinkle (in vivo) effect of combined formulation ...
Amal Kumar Ghimeray +5 more
semanticscholar +1 more source
Journal of Cell Biology, 1989 We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene expression in rabbit synovial fibroblasts. Monoclonal antibodies to the FnR that block initial adhesion of fibroblasts to fibronectin induced the expression of genes ...
Z. Werb +4 more
semanticscholar +1 more source
An efficient, economical slow-freezing method for large-scale human embryonic stem cell banking [PDF]
, 2012 Human embryonic stem cells (hESCs) are one of the most interesting cell types for tissue engineering, cell therapy, basic scientific research, and drug screening. Fast advancement in these areas requires the availability of large amounts of safe and well-
Cornelissen, Maria +3 more
core +2 more sources
Biochemical Characterization of Human Collagenase-3 (*)
Journal of Biological Chemistry, 1996 The cDNA of a novel matrix metalloproteinase, collagenase-3 (MMP-13) has been isolated from a breast tumor library (Freije, J. M. P., Diez-Itza, I., Balbin, M., Sanchez, L. M., Blasco, R., Tolivia, J., and López-Otin, C.(1994) J. Biol. Chem.
V. Knäuper +4 more
semanticscholar +1 more source