Results 61 to 70 of about 188,356 (306)

Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1 [PDF]

, 2000
Bachmeier BE, Nerlich AG, Boukamp P, et al. Human keratinocyte cell lines differ in the expression of the collagenolytic matrix metalloproteinases-1,-8, and-13 and of TIMP-1. BIOLOGICAL CHEMISTRY.
Boukamp, P, Tschesche, Harald, Bachmeier, BE, Bachmeier, B. E., Nerlich, A. G., Fink, E., Fritz, H, Fink, E, Fritz, H., Tschesche, H., Lichtinghagen, R., Nerlich, AG, Lichtinghagen, R, Boukamp, P.   +13 more
core   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Undervalued ubiquitous proteins

4 open, 2019
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Collagenase expression by normal human eosinophils

, 1998
Collagenolytic activity was detected in extracts from human blood eosinophilic granulocytes. To characterize this collagenase, we compared extracts from isolated populations of eosinophils and neutrophils.
Karen A Hasty, Boris V Shlopov
core   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Insight into the spoilage heterogeneity of meat-borne bacteria isolates with high-producing collagenase

Food Science and Human Wellness
Chilled chicken is inevitably contaminated by microorganisms during slaughtering and processing, resulting in spoilage. Cutting parts of chilled chicken, especially wings, feet, and other skin-on products, are abundant in collagen, which may be the ...
Haodong Wang, Liangting Shao, Jinhao Zhang, Xinglian Xu, Jianjun Li, Huhu Wang   +5 more
doaj   +1 more source

Studies on the regulation of extracellular collagenase production by vibrio alginolyticus

, 1981
Bibliography: leaves 117-133.Vibrio alginolyticus synthesized extracellular collagenase in a highly aerated peptone medium at the late-exponential and early-stationary phases of growth.
Reid, Graham Charlton
core  

LATENT COLLAGENASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES AND ACTIVATION TO COLLAGENASE BY REMOVAL OF AN INHIBITOR

, 1980
MACARTNEY HW, Tschesche H. LATENT COLLAGENASE FROM HUMAN POLYMORPHONUCLEAR LEUKOCYTES AND ACTIVATION TO COLLAGENASE BY REMOVAL OF AN INHIBITOR. FEBS LETTERS.
MACARTNEY, HW, Tschesche, Harald, Macartney, H.W., Tschesche, H., H. Tschesche, H.W. Macartney   +5 more
core   +1 more source

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

Advanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig, F. Max Yavitt, Laura Veenendaal, Tim B. F. Woodfield   +3 more
wiley   +1 more source

BIOSYNTHESIS OF INDUSTRIAL ENZYMES BY FREE AND IMMOBILIZED Alicyclobacillus spp IN DIFFERENT MATRICES AND THE USE OF ULTRAFILTRATION IN THE ENZYMES CONCENTRATION

Química Nova
The biosynthesis of amylase and collagenase, produced by A. acidocaldarius and A. sendaiensis respectively, were studied, and different matrices evaluated for the microorganisms immobilization and enzymes production optimization, such as loofa sponge ...
Suelen Pereira Ruiz, Juliana Harumi Miyoshi, Gabriela Gregolin Gimenez, Camila Ortiz Martinez, Benício Alves de Abreu Filho, Graciette Matioli   +5 more
doaj   +1 more source