Results 51 to 60 of about 188,356 (306)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

The role of collagenase in emphysema [PDF]

open access: yesRespiratory Research, 2001
The extracellular matrix is essential for the integrity of the lung and when disrupted can lead to the architectural changes seen in emphysema. The etiology of emphysema is believed to be due to an imbalance in the proteases and antiproteases within the lung.
Foronjy, Robert F.   +1 more
openaire   +4 more sources

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli   +17 more
wiley   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

open access: yesAdvanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse   +9 more
wiley   +1 more source

Comparison of two methods for determining human adipose cell size

open access: yesJournal of Lipid Research, 1972
The mean cell sizes of specimens of human adipose tissue were determined on sectioned slices according to the method described by Sjöström et al. (J. Lipid Res. 1971. 12: 521–530) and on adipocytes isolated after treatment of the tissue with collagenase.
Ulf Smith   +2 more
doaj   +1 more source

Regulation of 92-kD gelatinase release in HL-60 leukemia cells [PDF]

open access: yes, 1994
Matrix metalloproteinase 9 (MMP-9), also known as 92-kD type IV collagenase/gelatinase, is believed to play a critical role in tumor invasion and metastasis. Here, we report that MMP-9 was constitutively released from the human promyelocytic cell line HL-
Petrides, P. E.   +2 more
core  

Nanofibers versus hydrogels as collagenase carrier [PDF]

open access: yes, 2021
Collagenase acts by promoting wound debridement, contributing to the tissue repair process. Several studies pointed collagenase as a substance involved in the elimination of devitalized tissue or any contaminated material found in the wound bed after ...
Santos, Jorge   +4 more
core  

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad   +7 more
wiley   +1 more source

Localized co-delivery of collagenase and trastuzumab by thermosensitive hydrogels for enhanced antitumor efficacy in human breast xenograft

open access: yesDrug Delivery, 2018
Modulation of the collagen-rich extracellular matrix (ECM) in solid tumors by the treatment with collagenase has been proved effective in enhancement of the interstitial transport and antitumor efficacy of antibodies.
Anni Pan   +8 more
doaj   +1 more source

COLLAGENASE IN SJOGRENS-SYNDROME

open access: yes, 1994
KONTTINEN YT, KANGASPUNTA P, LINDY O, et al. COLLAGENASE IN SJOGRENS-SYNDROME. ANNALS OF THE RHEUMATIC DISEASES. 1994;53(12):836-839.Objective-To study collagenase production in labial salivary glands in patients with Sjogren's syndrome (SS).
Tschesche, Harald   +7 more
core   +1 more source

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