Results 71 to 80 of about 188,356 (306)

Degraded collagenase deteriorates islet viability.

, 2008
OBJECTIVE: The utilization of purified enzyme blends consisting of collagenase class I (CI) and II (CII) and neutral protease is an essential step for clinical islet isolation. Previous studies suggested that the use of enzyme lots containing degraded CI
Brandhorst, Daniel, Raemsch-Guenther, N., Korsgren, Olle,, Raemsch-Guenther, N, Korsgren, O, Friedrich, O., Kurfuerst, M, Brandhorst, Heide, Friedrich, O, Brandhorst, Daniel,, Brandhorst, Heide,, Raemsch, C, Kurfuerst, M., Raemsch, C.   +13 more
core   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Current Trends in the Treatment of Dupuytren Disease in Spain

Revista Iberoamericana de Cirugía de la Mano, 2020
Objective Assessment of the treatment trends of Spanish surgeons in clinical practice by making clinical assumptions in Dupuytren's disease (DD). Material and Method A survey was sent to the members of the Spanish Society for Surgery of the ...
Rafael Sanjuan-Cerveró, Diego Gómez-Herrero, Carlos Novoa-Parra, Fernando Peña-Molina, Nuria Franco-Ferrando   +4 more
doaj   +1 more source

Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin

, 1988
Type IV collagenase is a metalloproteinase associated with metastatic tumor cells. It specifically cleaves the triple helical basement membrane (type IV) collagen molecule at a single site. Monoclonal antibodies which block the activity of the human type
Lance A. Liotta, Höyhtyä, Matti, Liotta, Lance A., William Stetler-Stevenson, Henry Krutzsch, Karl Tryggvason, Stetler-Stevenson, William, Krutzsch, Henry, Matti Höyhtyä, Taina Turpeenniemi-Hujanen, Turpeenniemi-Hujanen, Taina, Tryggvason, Karl   +11 more
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Interlamellar cohesion after collagenase type II exposure in rabbit cornea

, 2015
Purpose: Collagenase could be considered as a method for generating animal model of keratoconus. The authors aimed to evaluate the impact of collagenase on the interlamellar cohesive force of rabbit corneas.
Song WJ, Rong B, Yang SL, Yan XM, Li HL, Qiao J, Tang Y, Wu Y, 印亚奇, Yin YQ(印亚奇)   +9 more
core  

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

Advanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu, Qizheng Zhang, Tianli Hu, Juewen Liu, Hongxing Fu, Xin Zhao, Zijiang Yang, Chenjie Xu   +7 more
wiley   +1 more source

Collagenase Activity in Cholesteatoma

ORL, 2010
Collagenase activity of cholesteatoma epithelium, temporal bone and ear canal skin was investigated. The enzyme extracted from these tissues was proved to be collagenase by disc electrophoresis. Collagenase activity was measured directly in homogenates of tissues. Activity was greatest in the skin.
Iwanaga, Michitaka, Yamamoto, Etsuo
openaire   +2 more sources