Results 51 to 60 of about 255,819 (284)

An investigation into the effectiveness of collagenase for the percutaneous discolysis of thoracolumbar intervertebral discs in the dog : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University [PDF]

open access: yes, 1993
This investigation compared the effectiveness of chemonucleolysis with 500 units of collagenase, to lateral fenestration of the thoracolumbar intervertebral discs of the non-chondrodystrophoid dog.
Bray, Jonathan Peter
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Immunotargeting of collagenase on thrombus

open access: yesInternational Journal of Nanomedicine, 2010
Yi-ling Lu, Ben-xia Yang, Zong-ning YinKey Laboratory of Drug Targeting and Delivery System, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaAbstract: In this study, we aimed to develop a thrombus ...
Yi-ling Lu, Ben-xia Yang, Zong-ning Yin
doaj  

Insights into Molecular Interaction of Flavonoid Compounds in Citrus Peel Bound to Collagenase and Elastase Enzymes: A Computational Study

open access: yesPharmaceutical Sciences and Research, 2021
Citrus peels contain various phytochemical active compounds such as flavonoids that are useful for antiaging cosmetic products. This study was conducted to identify the anti-collagenase and anti-elastase activities of flavonoid compounds in citrus peel ...
Sani Ega Priani, Taufik Muhammad Fakih
doaj   +1 more source

Ca2+ - Induced Structural Change of Multi-Domain Collagen Binding Segments of Collagenases ColG and ColH from Hathewaya histolytica [PDF]

open access: yes, 2018
Hathewaya histolytica, previously renamed as Clostridium histolyticum, secretes at least two collagenases, ColH and ColG, that allow for degradation of extracellular matrices of animal tissue.
Ruth, Christopher Eric
core   +2 more sources

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato   +9 more
wiley   +1 more source

Clinical and Ultrasonographic Findings of Collagenase Induced Tendinitis in the Horse [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2007
Objective- The aim of this study was to assess the clinical and ultrasonographic alterations in the superficial digital flexor tendon (SDFT) of horses with collagenase-induced tendinitis. Design- Experimental study.
Mohammad Mehdi Dehghan   +5 more
doaj  

Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages [PDF]

open access: yes, 2010
Oxygen is a critical parameter proposed to modulate the functions of chondrocytes ex-vivo as well as in damaged joints. This article investigates the effect of low (more physiological) oxygen percentage on the biosynthetic and catabolic activity of human
Ströbel, Simon   +8 more
core   +2 more sources

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Validation of a rapid collagenase activity detection technique based on fluorescent quenched gelatin with synovial fluid samples

open access: yesBMC Biotechnology
Background Measuring collagenase activity is crucial in the field of joint health and disease management. Collagenases, enzymes responsible for collagen degradation, play a vital role in maintaining the balance between collagen synthesis and breakdown in
Miguel de la Fuente   +6 more
doaj   +1 more source

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