Results 21 to 30 of about 20,337 (280)

Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana   +2 more
doaj   +1 more source

Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]

open access: yes, 2017
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet   +6 more
core   +3 more sources

Taxonomic and Enzymatic Characterization of Flocculibacter collagenilyticus gen. nov., sp. nov., a Novel Gammaproteobacterium With High Collagenase Production

open access: yesFrontiers in Microbiology, 2021
Collagens from marine animals are an important component of marine organic nitrogen. Collagenase-producing bacteria and their collagenases play important roles in collagen degradation and organic nitrogen recycling in the ocean.
Jian Li   +15 more
doaj   +1 more source

Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro

open access: yesCells, 2018
Background and Objective: YB-1 is a transcription and oncogenic factor capable of binding to DNA and RNA performing versatile functions within normal and cancer cells.
Wisam Nabeel Ibrahim   +2 more
doaj   +1 more source

Endogenous Collagenases Regulate Osteoclast Fusion

open access: yesBiomolecules, 2020
The precise regulation of osteoclast differentiation and function is crucial for the maintenance of healthy bone. Despite several reports of collagenase expression in bone tissues, the precise isoform expression as well as the role in osteoclasts are ...
Hyo Jeong Kim, Youngkyun Lee
doaj   +1 more source

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease [PDF]

open access: yes, 2010
Oxidative stress is proposed as an important factor in osteoarthritis (OA). To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA.
Boot-Handford, Raymond P.   +9 more
core   +1 more source

Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]

open access: yes, 2012
Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany   +7 more
core   +2 more sources

Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

open access: yesCell Reports, 2017
Physiologic turnover of interstitial collagen is mediated by a sequential pathway in which collagen is fragmented by pericellular collagenases, endocytosed by collagen receptors, and routed to lysosomes for degradation by cathepsins.
Daniel Hargbøl Madsen   +9 more
doaj   +1 more source

Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation

open access: yesJournal of Diabetes Research, 2016
The clostridial collagenases, H and G, play key roles in pancreatic islet isolation. Collagenases digest the peptide bond between Yaa and the subsequent Gly in Gly-Xaa-Yaa repeats.
Hiroki Shima   +7 more
doaj   +1 more source

Gene expression and matrix turnover in overused and damaged tendons [PDF]

open access: yes, 2005
Chronic, painful conditions affecting tendons, frequently known as tendinopathy, are very common types of sporting injury. The tendon extracellular matrix is substantially altered in tendinopathy, and these changes are thought to precede and underlie the
Abbaszade I   +97 more
core   +1 more source

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