Results 161 to 170 of about 7,134 (210)

Functional Roles of the Complement Immune System in Cardiac Inflammation and Hypertrophy. [PDF]

Int J Mol Sci
Hok KD, Rich HE, Shadid A, Gunamalai L, Weng-Mills T, Thandavarayan RA, Banda NK, Doursout MF, Restrepo MI, Shivshankar P.   +9 more
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A collectin-like protein from tunicates

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2000
Collectins are a sub-family of C-type lectins from mammals and birds that are characterized by their collagen-like domains. The mammalian collectin, mannose binding lectin, has attracted considerable interest because it can activate complement components via a lectin-mediated complement pathway that is independent of immunoglobulins.
Sham V Nair, P L Green, D A Raftos
exaly   +3 more sources

The collectins in innate immunity

Current Opinion in Immunology, 1996
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
J, Epstein, Q, Eichbaum, S, Sheriff, R A, Ezekowitz   +3 more
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Collectins and viral infection

Trends in Microbiology, 1995
Members of the collectin protein family are beta-inhibitors of influenza virus infectivity. They bind to carbohydrate on the surface of influenza virus and sterically inhibit virus interaction with host cells, and may also act as opsonins. We propose that collectins, by interacting with glycosylated viruses, act as innate inhibitors of viral infection.
R, Malhotra, R B, Sim
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Expanded collectin family in bullfrog (Rana catesbeiana): Identification and characterization of plasma collectins

Developmental & Comparative Immunology, 2021
BLAST searches against databases for the bullfrog (Rana catesbeiana), using the collectin sequence previously identified in tadpoles, revealed the presence of at least 20 members of the collectin gene family. Phylogenetic analysis demonstrated that the bullfrog possesses expanded gene subfamilies encoding mannose-binding lectin (MBL) and pulmonary ...
Masako, Okada, Takanori, Akimoto, Akinori, Ishihara, Kiyoshi, Yamauchi   +3 more
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Surfactant Collectins and Innate Immunity

Neonatology, 2008
Respiratory pathogens encounter various lines of defenses before infection of the host is established. The innate immune response represents an important first-line protection mechanism against potentially pathogenic microorganisms during early stages of infection of the naive host.
Haagsman, H.P., Hogenkamp, A., van Eijk, M., Veldhuizen, E.J.A.   +3 more
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Collectins and collectin receptors in innate immunity

APMIS, 2000
This thesis is based on nine papers and a review on the collectins and collectin receptors in innate immunity. The collectins are a family of proteins in which the individual chains consist of a C-type lectin domain attached to a collagen domain via an alpha-coiled neck region.
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The Role of Collectins in Host Defense

Seminars in Liver Disease, 1997
Mannose-binding protein (MBP) belongs to a group of Ca(2+)-dependent lectins called collectins that play a role in first-line host defense. It recognizes specific carbohydrate residues (mannose and N-acetylglucosamine) on the surface of microorganisms and promotes the killing of microbes either by acting directly as an opsonin or by activating the ...
M, Sumiya, J A, Summerfield
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Collectins: sentinels of innate immunity

BioEssays, 2007
AbstractCollectins, present in plasma and on mucosal surfaces, are humoral molecules of the innate immune system. They were discovered a hundred years ago in 1906 as the first association of an animal lectin with the immune system. They are a family of calcium‐dependent lectins that recognize pathogen‐associated molecular patterns. They share a similar
Gupta, Garima, Surolia, Avadhesha
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The Pulmonary Collectins and Surfactant Metabolism

Annual Review of Physiology, 2001
▪ Abstract  Lung surfactant covers and stabilizes a large, delicate surface at the interface between the host and the environment. The surfactant system is placed at risk by a number of environmental challenges such as inflammation, infection, or oxidant stress, and perhaps not surprisingly, it demonstrates adaptive changes in metabolism in response to
S, Hawgood, F R, Poulain
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