Collectins and ficolins in neonatal health and disease [PDF]
Frontiers in Immunology, 2023 The immune system starts to develop early in embryogenesis. However, at birth it is still immature and associated with high susceptibility to infection.
Maciej Cedzyński, Anna S. Świerzko
doaj +4 more sources
A Plausible Role for Collectins in Skin Immune Homeostasis [PDF]
Frontiers in Immunology, 2021 The skin is a complex organ that faces the external environment and participates in the innate immune system. Skin immune homeostasis is necessary to defend against external microorganisms and to recover from stress to the skin.
Ke Li, Shengxiang Xiao, Yumin Xia
exaly +4 more sources
Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates [PDF]
Frontiers in ImmunologyIntroductionPremature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory distress.
Gabriela Gajek +13 more
doaj +6 more sources
Promoting immune defensive responses of epithelial cells in airway disease [PDF]
Frontiers in AllergyThe airway epithelium serves as both a physical barrier and as an active contributor in maintaining immune defense. Upon exposure to external insults such as injury and infection, the epithelium releases alarmins including interleukin-25 (IL-25), IL-33 ...
Michael J. Parnham +2 more
doaj +2 more sources
Differential expression of collectins in human placenta and role in inflammation during spontaneous labor. [PDF]
PLoS ONE, 2014 Collectins, collagen-containing Ca(2+) dependent C-type lectins and a class of secretory proteins including SP-A, SP-D and MBL, are integral to immunomodulation and innate immune defense.
Ajit Kumar Yadav +6 more
doaj +8 more sources
Gene expression profiling of liver from dairy cows treated intra-mammary with lipopolysaccharide [PDF]
BMC Genomics, 2008 Background Liver plays a profound role in the acute phase response (APR) observed in the early phase of acute bovine mastitis caused by Escherichia coli (E. coli).
Vels Lotte +4 more
doaj +2 more sources
Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome. [PDF]
, 2012 The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional properties and could thereby influence clinical status in patients with lung diseases.
Ballmann, Manfred +7 more
core +20 more sources
Frontiers in Immunology, 2022 Lung surfactant protein D (SP-D) and Dendritic cell-specific intercellular adhesion molecules-3 grabbing non-integrin (DC-SIGN) are pathogen recognising C-type lectin receptors.
Nazar Beirag +13 more
doaj +1 more source
On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx [PDF]
, 2020 Gas exchange in the lung takes place via the air-blood barrier in the septal walls of alveoli. The tissue elements that oxygen molecules have to cross are the alveolar epithelium, the interstitium and the capillary endothelium.
Hegermann, Jan +8 more
core +1 more source
Transcriptional expression levels of chicken collectins are affected by avian influenza A virus inoculation [PDF]
, 2010 Mammalian collectins have been found to play an important role in the defense against influenza A virus H9N2 inoculation, but for chicken collectins this has not yet been clarified.
Cherina Fleming +28 more
core +11 more sources