Results 11 to 20 of about 5,247 (206)

Collectins [PDF]

open access: yesEuropean Journal of Biochemistry, 2004
Collectins are a family of collagenous calcium‐dependent defense lectins in animals. Their polypeptide chains consist of four regions: a cysteine‐rich N‐terminal domain, a collagen‐like region, an α‐helical coiled‐coil neck domain and a C‐terminal lectin or carbohydrate‐recognition domain.
van de Wetering, J.K.   +2 more
openaire   +3 more sources

Collectin structure: A review [PDF]

open access: yesProtein Science, 2000
AbstractColleetins are animal calcium dependent lectins that target the carbohydrate structures on invading pathogens, resulting in the agglutination and enhanced clearance of the microorganism. These proteins form trimers that may assemble into larger oligomers.
K, Håkansson, K B, Reid
openaire   +2 more sources

The role of surfactant proteins SP-A and SP-D in viral infection: a focus on COVID-19

open access: yesБюллетень сибирской медицины, 2022
An immune response to invasion of viral pathogens is an integral part of maintaining the physiological functioning of the bronchopulmonary system and effective gas exchange.
O. S. Kharlamovа   +2 more
doaj   +1 more source

Endothelial Glycocalyx: The Missing Link Between Angiogenic Imbalance in Preeclampsia and Systemic Inflammation in HELLP Syndrome. [PDF]

open access: yesCompr Physiol
Endothelial glycocalyx may be the missing link between angiogenic factors, inflammatory regulation, and endothelial maternal dysfunction in early‐onset preeclampsia and HELLP syndrome. ABSTRACT The pathophysiology of preeclampsia and HELLP syndrome relies on systemic vascular endothelial dysfunction, resulting from angiogenic imbalance due to abnormal ...
Atallah A   +4 more
europepmc   +2 more sources

Investigations on Collectin Liver 1 [PDF]

open access: yesJournal of Biological Chemistry, 2013
Collectins are pattern recognition molecules of the innate immune system showing binding to carbohydrate structures on microorganisms in a calcium-dependent manner. Recently, three novel collectins, collectin liver 1 (CL-L1), collectin kidney 1 (CL-K1 and CL-11), and collectin placenta 1 (CL-P1), were discovered.
Axelgaard, Esben   +6 more
openaire   +2 more sources

Proteins of the lectin pathway of the complement system activation: immunobiological functions, genetics and involvement in the pathogenesis of human diseases

open access: yesИнфекция и иммунитет, 2022
The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova   +1 more
doaj   +1 more source

Ancient origins: complement in invertebrates [PDF]

open access: yesInvertebrate Survival Journal, 2005
Proteins with obvious similarities to mammalian complement are widely distributed in the animal kingdom.In the vertebrate lineage, deuterostomes like sea urchins and tunicates express proteins that arehomologues of C3, the central component of the ...
SV Nair, A Ramsden, DA Raftos
doaj   +2 more sources

Structural Aspects of Collectins and Receptors for Collectins

open access: yesImmunobiology, 1998
The collectins are oligomeric molecules composed of C-type lectin domains attached to collagen regions via alpha-coiled neck regions. Five members of the collectins have been characterized. Mannan-binding lectin (MBL), conglutinin and collectin-43 (CL-43) are serum proteins produced by the liver.
S, Hansen, U, Holmskov
openaire   +2 more sources

The Dual Role of Surfactant Protein-D in Vascular Inflammation and Development of Cardiovascular Disease

open access: yesFrontiers in Immunology, 2019
Cardiovascular disease (CVD) is responsible for 31% of all global deaths. Atherosclerosis is the major cause of cardiovascular disease and is a chronic inflammatory disorder in the arteries.
Kimmie B. Colmorten   +2 more
doaj   +1 more source

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