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Collectins are a family of collagenous calcium‐dependent defense lectins in animals. Their polypeptide chains consist of four regions: a cysteine‐rich N‐terminal domain, a collagen‐like region, an α‐helical coiled‐coil neck domain and a C‐terminal lectin or carbohydrate‐recognition domain.
van de Wetering, J.K. +2 more
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Collectin structure: A review [PDF]
AbstractColleetins are animal calcium dependent lectins that target the carbohydrate structures on invading pathogens, resulting in the agglutination and enhanced clearance of the microorganism. These proteins form trimers that may assemble into larger oligomers.
K, Håkansson, K B, Reid
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The role of surfactant proteins SP-A and SP-D in viral infection: a focus on COVID-19
An immune response to invasion of viral pathogens is an integral part of maintaining the physiological functioning of the bronchopulmonary system and effective gas exchange.
O. S. Kharlamovа +2 more
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Complement and transplant‐associated thrombotic microangiopathy: Current and future approaches [PDF]
HemaSphere, Volume 10, Issue 4, April 2026.
Cugno M, Onida F, Lämmle B.
europepmc +2 more sources
Endothelial Glycocalyx: The Missing Link Between Angiogenic Imbalance in Preeclampsia and Systemic Inflammation in HELLP Syndrome. [PDF]
Endothelial glycocalyx may be the missing link between angiogenic factors, inflammatory regulation, and endothelial maternal dysfunction in early‐onset preeclampsia and HELLP syndrome. ABSTRACT The pathophysiology of preeclampsia and HELLP syndrome relies on systemic vascular endothelial dysfunction, resulting from angiogenic imbalance due to abnormal ...
Atallah A +4 more
europepmc +2 more sources
Investigations on Collectin Liver 1 [PDF]
Collectins are pattern recognition molecules of the innate immune system showing binding to carbohydrate structures on microorganisms in a calcium-dependent manner. Recently, three novel collectins, collectin liver 1 (CL-L1), collectin kidney 1 (CL-K1 and CL-11), and collectin placenta 1 (CL-P1), were discovered.
Axelgaard, Esben +6 more
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The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova +1 more
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Ancient origins: complement in invertebrates [PDF]
Proteins with obvious similarities to mammalian complement are widely distributed in the animal kingdom.In the vertebrate lineage, deuterostomes like sea urchins and tunicates express proteins that arehomologues of C3, the central component of the ...
SV Nair, A Ramsden, DA Raftos
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Structural Aspects of Collectins and Receptors for Collectins
The collectins are oligomeric molecules composed of C-type lectin domains attached to collagen regions via alpha-coiled neck regions. Five members of the collectins have been characterized. Mannan-binding lectin (MBL), conglutinin and collectin-43 (CL-43) are serum proteins produced by the liver.
S, Hansen, U, Holmskov
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Cardiovascular disease (CVD) is responsible for 31% of all global deaths. Atherosclerosis is the major cause of cardiovascular disease and is a chronic inflammatory disorder in the arteries.
Kimmie B. Colmorten +2 more
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