Results 1 to 10 of about 9,026,275 (240)
Pharmaceutics, 2022 In situ calcium pectinate-coated pellets were proposed by applying an alternate coating method to drug-layered pellets to achieve colon-specific drug delivery.
Pimphaka Wanasawas +2 more
doaj +4 more sources
International Journal of Nanomedicine, 2018 Yao-Yao Yang,1,* Zhe-Peng Liu,2,* Deng-Guang Yu,1 Ke Wang,1 Ping Liu,1 Xiaohong Chen1 1School of Materials Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China; 2School of Medical Instrument and Food Engineering ...
Yang Y +5 more
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FORMULATION AND EVALUATION OF A COLON DRUG DELIVERY SYSTEM CONTAINING DIFLUNISAL [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2014 Oral drug delivery is the most desirable and preferred method of administering therapeutic agents for providing both systemic and local effects in various parts of the gastrointestinal tract.
Samar Mayah +3 more
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Nanostructured Chitosan-Based Biomaterials for Sustained and Colon-Specific Resveratrol Release [PDF]
International Journal of Molecular Sciences, 2019 In the present work, we demonstrate the preparation of chitosan-based composites as vehicles of the natural occurring multi-drug resveratrol (RES). Such systems are endowed with potential therapeutic effects on inflammatory bowel diseases (IBD), such as Crohn’s disease (CD) and ulcerative colitis, through the sustained colonic release of RES from long ...
Nieves Iglesias +5 more
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Development and evaluation of colon-specific releasing nanoemulsion/hydrogel pellets of camptothecin
Acta Poloniae Pharmaceutica - Drug Research, 2022 Camptothecin-loaded nanoemulsion (CPT/NE), sodium alginate, carbomer and calcium chloride were chosen to prepare camptothecin-loaded nanoemulsion / hydrogel (CPT/NE/HG) pellets. The optimal formulation of CPT/NE/HG pellets was composed of a mixture of the CPT/NE to hydrogel (1:1, w/w) followed by solidification with 15.0% CaCl2 solution, and the ...
Yanbin Shi +9 more
openaire +1 more source
Studies on Jackfruit–Okra Mucilage-Based Curcumin Mucoadhesive Tablet for Colon Targeted Delivery
Frontiers in Pharmacology, 2022 The present work investigates a blend of jack fruit mucilage (JFM) and okra mucilage (OKM) as promising mucoadhesive carriers for colon-specific delivery of a curcumin (CMN)-loaded mucoadhesive tablet (CMT) formulation.
Pallavi Kurra +8 more
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Journal of Nanobiotechnology, 2023 Colon-targeted oral drug delivery systems (CDDSs) are desirable for the treatment of ulcerative colitis (UC), which is a disease with high relapse and remission rates associated with immune system inflammation and dysregulation localized within the ...
Yipeng Zhang +7 more
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Recent advances in mesalamine colonic delivery systems
Future Journal of Pharmaceutical Sciences, 2020 Background Increased attention has been focused on the continuous development and improvement of mesalamine colonic specific delivery systems, for the effective treatment of inflammatory bowel diseases; thus enhancing therapeutic efficacy and reducing ...
Mohammad F. Bayan, Rana F. Bayan
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Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. [PDF]
PLoS ONE, 2012 Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, information ...
Lihong Wang +10 more
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Advances in orally targeted drug delivery to colon
Journal of Advanced Pharmaceutical Technology & Research, 2019 Colon-specific drug delivery is critical for treating diseases of colon, such as colon cancer, amoebiasis, irritable bowel syndrome, and inflammatory bowel disease. This study reviews the effects of targeted oral drug delivery on patient by measuring the
Nagina Belali +2 more
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