Results 11 to 20 of about 9,026,275 (240)

Quality by Design (QbD) Approach to Develop Colon-Specific Ketoprofen Hot-Melt Extruded Pellets: Impact of Eudragit® S 100 Coating on the In Vitro Drug Release

open access: yesPharmaceutics
Background: A pelletizer paired with hot-melt extrusion technology (HME) was used to develop colon-targeted pellets for ketoprofen (KTP). Thermal stability and side effects in the upper gastrointestinal tract made ketoprofen more suitable for this work ...
Sateesh Kumar Vemula   +9 more
doaj   +2 more sources

Microencapsulation of Clostridium difficile specific bacteriophage using glass microcapillary devices and pH dependent controlled release for colon targeted delivery [Abstract] [PDF]

open access: yes, 2016
Microencapsulation of Clostridium difficile specific bacteriophage using glass microcapillary devices and pH dependent controlled release for colon targeted delivery ...
Danish Malik (1254321)   +3 more
core   +5 more sources

Clostridium difficile specific bacteriophage microencapsulation within porous Eudragit particles and pH dependent controlled release for colon targeted delivery [Abstract] [PDF]

open access: yes, 2016
Clostridium difficile specific bacteriophage microencapsulation within porous Eudragit particles and pH dependent controlled release for colon targeted delivery ...
Danish Malik (1254321)   +3 more
core   +5 more sources

An investigation into liposomal formulations for targeted drug delivery to the colon [PDF]

open access: yes, 2012
Recent studies have shown the numerous advantages associated with specific drug delivery to the colon, highlighting its favourable conditions and long transit time as the main advantages.
Barea, Matthew Ernest John
core   +7 more sources

Levan in the developing of new colon-specific polymer material: evaluation of the permeability, moisture and thermal analyses in free films of Eudragit® FS 30 D - doi 10.4025/actascihealthsci.v34i2.11729

open access: yesActa Scientiarum. Health Sciences, 2012
Levan was used as agent in the synthesis of new colon-specific polymeric matrix together with Eudragit® FS 30 D. Eudragit® FS 30 D films incorporated with levan were made by casting process and characterized to: water vapour transmission, sweeling index,
Maria Antonia Pedrine Colabone Celligoi   +4 more
doaj   +3 more sources

Chitosan-capped enzyme-responsive hollow mesoporous silica nanoplatforms for colon-specific drug delivery

open access: yesNanoscale Research Letters, 2020
An enzyme-responsive colon-specific delivery system was developed based on hollow mesoporous silica spheres (HMSS) to which biodegradable chitosan (CS) was attached via cleavable azo bonds (HMSS–N=N–CS).
Defu Cai   +9 more
doaj   +1 more source

Formulation development and in-vitro evaluation of Molsidomine matrix tablets for colon specific release

open access: yesJournal of Drug Delivery and Therapeutics, 2020
Colon targeted tablets were prepared in two steps. Initially core tablets were prepared and then the tablets were coated by using different pH dependent polymers. Ethyl cellulose, Eudragit L100 and S100 were used as coating polymers. FT-IR studies were carried out to find out the possible interaction between the selected drugs and polymer.
Lohithasu Duppala   +3 more
openaire   +2 more sources

Development and in-vitro evaluation of a colon-specific controlled release drug delivery system

open access: yesJournal of Pharmacy and Pharmacology, 2008
Abstract The major challenges in targeting drug to various parts of the gastrointestinal tract include control of drug release with respect to its environment and transit time. These two variables should be taken into consideration in designing a rational colonic drug delivery system. To this end, a swelling matrix core containing pectin,
Rahmat M, Talukder, Reza, Fassihi
openaire   +2 more sources

Encapsulation of Marjoram Phenolic Compounds Using Chitosan to Improve Its Colon Delivery

open access: yesFoods, 2022
In this study, chitosan particles were used to encapsulate marjoram phenolic compounds as colon-specific drug-delivery systems. The microparticles were prepared by ionic gelation and spray-drying techniques and varying amounts of polymer and extract ...
María de las Nieves Siles-Sánchez   +3 more
doaj   +1 more source

Colon Targeted Delivery Dosage Forms for Probiotics: A Review

open access: yesPharmaceutical Sciences and Research, 2023
Encapsulation was a promising method for protecting probiotics from extreme conditions during their passage through the gastrointestinal tract and delivering probiotics to specific sites in the colon for colonization.
Gede Anom Anjasmara   +2 more
doaj   +1 more source

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