Results 31 to 40 of about 982,011 (308)
Survival analysis for colon subsite and rectal cancers: Experience from a single surgeon [PDF]
Korean Journal of Clinical Oncology, 2015 Purpose: The survival rates of patients with colorectal cancers have been well documented in many studies. Some studies have shown that proximal colon cancers have inferior survival rates when compared with distal colon cancers.
Inhwa Lee +5 more
doaj +1 more source
Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]
, 2009 <b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson +41 more
core +1 more source
Annals of Gastroenterological Surgery, 2020 Aim To investigate the effectiveness of the institutional medical structure and of the implemented clinical practice guidelines for improving colon cancer surgical outcomes.
Hirotoshi Kobayashi +8 more
doaj +1 more source
Canadian Journal of Gastroenterology, 1997 Hereditary colon cancer comprises approximately 10% of total colon cancer, a disease that affects 6% of the North American population. Knowledge of molecular genetics of familial adenomatous polyposis and hereditary nonpolyposis colon cancer has improved our diagnostic abilities and management, as well as furthered our understanding of the mechanisms ...
openaire +3 more sources
Colonic Cancer and Acromegaly [PDF]
Frontiers in Endocrinology, 2019 Acromegaly results in a significantly increased morbidity and mortality due to cardiovascular and respiratory complications, as well as malignancies arising mainly from the colon. Furthermore, an increased lifetime risk of malignant transformation of pre-malignant colonic lesions relates to a worse overall prognosis from colorectal cancer, which is ...
Dorota Dworakowska +4 more
openaire +3 more sources
Predictive biomarkers of colon cancer immunotherapy: Present and future
Frontiers in Immunology, 2022 Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors (ICIs) have shown clinical benefits for colon cancer patients, especially those with high microsatellite instability (MSI-H).
Wanting Hou, Cheng Yi, Hong Zhu
doaj +1 more source
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene
Cancer Medicine, 2019 Here, we investigated the clinicopathological and mutation profiles of colorectal cancer (CRC) with POLE mutations. Whole‐exome sequencing was performed in 910 surgically resected primary CRCs.
Hitoshi Hino +11 more
doaj +1 more source
Breast, colon, and prostate screening in the adult population of Croatia: does rural origin matter? [PDF]
, 2007 INTRODUCTION: The aim of this study was to investigate the utilization of breast, colon and prostate cancer screening in the adult Croatian population in a period without national cancer screening programs, with a special interest in respondents' rural ...
Kern, Josipa +5 more
core
E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]
, 2015 Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke +27 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source