Results 41 to 50 of about 5,799,531 (403)

Cetuximab in colon cancer [PDF]

The International Journal of Biological Markers, 2007
In the last decade remarkable progress has been made in the treatment of metastatic colorectal cancer due to the introduction of oxaliplatin and irinotecan in clinical practice. The addition of biological agents seems to offer a chance to further enhance the activity of conventional chemotherapy.
F, Giuliani, G, Colucci
openaire   +3 more sources

Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer.

JAMA Oncology, 2019
Importance Adjuvant chemotherapy in patients with stage III colon cancer prevents recurrence by eradicating minimal residual disease. However, which patients remain at high risk of recurrence after completing standard adjuvant treatment cannot currently ...
J. Tie, J. Cohen, Yuxuan Wang, M. Christie, K. Simons, Margaret Lee, R. Wong, S. Kosmider, Sumitra S Ananda, J. Mckendrick, Belinda Lee, J. Cho, I. Faragher, I. Jones, Janine Ptak, M. J. Schaeffer, Natalie Silliman, L. Dobbyn, Lu Li, C. Tomasetti, N. Papadopoulos, K. Kinzler, B. Vogelstein, P. Gibbs   +23 more
semanticscholar   +1 more source

An Observational Study of Trifluridine/Tipiracil-Containing Regimen Versus Regorafenib-Containing Regimen in Patients With Metastatic Colorectal Cancer

Frontiers in Oncology, 2022
BackgroundThere are no randomized control trials comparing the efficacy of trifluridine/tipiracil and regorafenib in patients with metastatic colorectal cancer (mCRC).
Meng-Che Hsieh, Meng-Che Hsieh, Kun-Ming Rau, Kun-Ming Rau, Shung-Eing Lin, Shung-Eing Lin, Kuang-Wen Liu, Kuang-Wen Liu, Chong-Chi Chiu, Chong-Chi Chiu, Chih-I Chen, Chih-I Chen, Ling-Chiao Song, Ling-Chiao Song, Hsin-Pao Chen, Hsin-Pao Chen   +15 more
doaj   +1 more source

The function of Piezo1 in colon cancer metastasis and its potential regulatory mechanism

Journal of Cancer Research and Clinical Oncology, 2020
Objective Increasing evidence has revealed that mechanical stress and elevated mechanical signals promote malignant tumor transformation and metastasis.
Yanhua Sun, Ming Li, Guangjie Liu, Xue Zhang, Lianghui Zhi, J. Zhao, Guiying Wang   +6 more
semanticscholar   +1 more source

Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats [PDF]

, 2003
High intake of red meat, but not of white meat, is associated with an increased risk of colon cancer. However, red meat does not promote cancer in rodents.
Corpet, Denis E., Petit, Claude, Pierre, Fabrice, Taché, Sylviane, Van der Meer, Roleof   +4 more
core   +5 more sources

Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology.

The Journal of the National Comprehensive Cancer Network
Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of cancer death in the United States. Management of disseminated metastatic CRC involves various active drugs, either in combination or as single agents ...
Al B. Benson, A. Venook, Mohamed Adam, George J. Chang, Yi-Jen Chen, K. K. Ciombor, Stacey A Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L Grem, Paul Haste, J. R. Hecht, Sarah Hoffe, S. Hunt, Hisham Hussan, K. Johung, Nora Joseph, Natalie N. Kirilcuk, S. Krishnamurthi, Midhun Malla, Jennifer K Maratt, W. Messersmith, J. Meyerhardt, E. D. Miller, M. Mulcahy, Steven J. Nurkin, M. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, Benjamin Shogan, J. Skibber, Constantinos T Sofocleous, Anna Tavakkoli, Christopher G. Willett, Christina Wu, Lisa A. Gurski, Jenna Snedeker, Frankie Jones   +42 more
semanticscholar   +1 more source

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model. [PDF]

, 2015
Colon cancer liver metastasis is often the lethal aspect of this disease. Well-isolated metastases are candidates for surgical resection, but recurrence is common. Better adjuvant treatment is therefore needed to reduce or prevent recurrence.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Murakami, Takashi, Tanaka, Kuniya, Zhang, Yong, Zhao, Ming   +8 more
core   +5 more sources

FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport

Cancer Cell International, 2020
Background The prognosis of colon cancer is poor for metastasis, while the mechanism, especially adipocytes related, is not yet clear. The purpose of this study is to determine the effects of fatty acid binding protein 4 (FABP4), a transporter for lipids,
Wenying Tian, Wenjia Zhang, Y. Zhang, T. Zhu, Yuting Hua, Hui Li, Qingling Zhang, M. Xia   +7 more
semanticscholar   +1 more source

Survival analysis for colon subsite and rectal cancers: Experience from a single surgeon [PDF]

Korean Journal of Clinical Oncology, 2015
Purpose: The survival rates of patients with colorectal cancers have been well documented in many studies. Some studies have shown that proximal colon cancers have inferior survival rates when compared with distal colon cancers.
Inhwa Lee, Seung-Hyun Baek, Hyunsung Kim, Hong-Jae Jo, Nahm-Gun Oh, Sanghwa Ko   +5 more
doaj   +1 more source

Impact of adherence to board‐certified surgeon systems and clinical practice guidelines on colon cancer surgical outcomes in Japan: A questionnaire survey of the National Clinical Database

Annals of Gastroenterological Surgery, 2020
Aim To investigate the effectiveness of the institutional medical structure and of the implemented clinical practice guidelines for improving colon cancer surgical outcomes.
Hirotoshi Kobayashi, Hiroyuki Yamamoto, Hiroaki Miyata, Mitsukazu Gotoh, Kenjiro Kotake, Kenichi Sugihara, Yasushi Toh, Yoshihiro Kakeji, Yasuyuki Seto   +8 more
doaj   +1 more source