Results 21 to 30 of about 172,583 (288)

Sex-Gender Differences in the Effectiveness of Treatment of Irritable Bowel Syndrome: A Systematic Review

open access: yesInternational Journal of General Medicine, 2021
Lente van Kessel, Doreth Teunissen, Toine Lagro-Janssen Department of Primary and Community Care / Gender and Women’s Health, Radboud University Medical Centre, Nijmegen, the NetherlandsCorrespondence: Lente van Kessel Multatuliplaats 18A, Nijmegen,
van Kessel L   +2 more
doaj  

Guidelines for inflammation models in mice for food components

open access: yeseFood, 2022
Inflammation is one of the major health threats to humans, and it is associated with various chronic diseases, including metabolic syndrome, type 2 diabetes, cardiovascular diseases, and several types of cancer.
Yanhui Han   +3 more
doaj   +1 more source

Rapid establishment of human colonic organoid knockout lines

open access: yesSTAR Protocols, 2022
Summary: Human colonic organoids derived from biopsy or autopsy tissues are a vital tool to study mucosal homeostasis, model colonic diseases, and develop therapeutics. Rapid and reliable generation of knockout organoid lines from multiple donors enables
Wei Gu   +4 more
doaj   +1 more source

Volvulus U-Shaped transverse colonic duplication: Report of a case and literature review

open access: yesJournal of Pediatric Surgery Case Reports, 2017
Tubular duplication of the colon is very rare especially in adulthood, because it is frequently symptomatic earlier in newborn life, so only few cases are reported in literature. Several theories are proposed to explain the onset and the evolution of gut
Ruankha Bilommi
doaj   +1 more source

Establishment of porcine and monkey colonic organoids for drug toxicity study

open access: yesCell Regeneration, 2021
Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li   +7 more
doaj   +1 more source

Abnormal Promoter Methylation of Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) Gene in the Pathogenesis of Crohn’s Disease

open access: yesActa Medica Iranica, 2023
Changes in the expression of nucleotide-binding oligomerization domain containing 2 (NOD2) play an important role in the pathogenesis of several autoimmune diseases, such as inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ...
Golshid Sanati   +6 more
doaj   +1 more source

Pharmacogenetics and diseases of the colon [PDF]

open access: yesCurrent Opinion in Gastroenterology, 2007
The deciphering of the human genome sequence has enabled the identification of genetic polymorphisms that are responsible for inter-individual variation in the response to drug therapy. This field is referred to as pharmacogenetics. We review the impact of pharmacogenetics on therapy in diseases of the colon using three common variant enzyme systems as
Irfan M Hisamuddin   +2 more
openaire   +3 more sources

Endoscopic Management of Benign Colonic Obstruction and Pseudo-Obstruction [PDF]

open access: yesClinical Endoscopy, 2020
There are a variety of causes of intestinal obstruction, with the most common cause being malignant diseases; however, volvulus, inflammatory bowel disease or diverticulitis, radiation injury, ischemia, and pseudo-obstruction can also cause colonic ...
Su Jin Jeong, Jongha Park
doaj   +1 more source

Helicobacter pylori and colorectal neoplasms: a concise review [PDF]

open access: yesArquivos de Gastroenterologia, 2021
Helicobacter pylori is the main etiological agent of all malignant tumors caused by an infectious disease. It is a major, at times dominant, factor in the pathogenesis of a large spectrum of diseases such as acute and chronic gastritis, gastric and ...
Luiz Gonzaga Vaz COELHO   +1 more
doaj   +1 more source

Maternal antibiotic-induced early changes in microbial colonization selectively modulate colonic permeability and inducible heat shock proteins, and digesta concentrations of alkaline phosphatase and TLR-stimulants in swine offspring. [PDF]

open access: yesPLoS ONE, 2015
Elevated intake of high energy diets is a risk factor for the development of metabolic diseases and obesity. High fat diets cause alterations in colonic microbiota composition and increase gut permeability to bacterial lipopolysaccharide, and subsequent ...
Marie-Edith Arnal   +4 more
doaj   +1 more source

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