Results 141 to 150 of about 1,557 (180)

Analysis of 1,25-dihydroxyvitamin D genomic action in human enteroids and colonoids reveals multiple regulatory effects of vitamin D in human intestinal physiology. [PDF]

Front Endocrinol (Lausanne)
Criss ZK, Deans-Fielder K, Fleet JC, Christakos S, Shroyer N.   +4 more
europepmc   +1 more source

Autophagy inhibition improves sensitivity to the multi-kinase inhibitor regorafenib in preclinical mouse colon tumoroids. [PDF]

Front Cell Dev Biol
Agostini G, Leprovots M, Jeandriens J, Lefort A, Libert F, Sclafani F, Langer I, Hendlisz A, Garcia MI.   +8 more
europepmc   +1 more source

Neuronal ALKAL2 and its ALK receptor contribute to the development of colitis-associated colorectal cancer. [PDF]

Proc Natl Acad Sci U S A
Delanne-Cuménal M, Defaye M, Delanne-Cuménal A, Ahmed M, Ho V, Abdullah NS, Alhassoun M, Svendsen K, Mager L, Schlessinger J, Hirota S, Altier C.   +11 more
europepmc   +1 more source

Ion transport and epithelial barrier dysfunction in experimental models of ulcerative colitis. [PDF]

Am J Physiol Gastrointest Liver Physiol
Sandle GI, Rajendran VM.
europepmc   +1 more source

Epithelial genetic muscarinic receptor 3 ablation induces sex-specific modulation of colonic intestinal progenitor cells and response to intestinal injury. [PDF]

J Crohns Colitis
Ragab M, Wieland J, Waldherr Avila de Melo C, Agibalova T, Ermolova A, Durner N, Hempel A, Heindl F, Maurer HC, Steiger K, Janssen KP, Tschurtschenthaler M, Wang TC, Quante M, Schmid RM, Middelhoff M.   +15 more
europepmc   +1 more source

Intestinal organoid models as tools to interrogate the physiology of human mucosal tissues and host-microbe interactions. [PDF]

mSphere
Lemme-Dumit JM.
europepmc   +1 more source

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease. [PDF]

Signal Transduct Target Ther
Oh MK, Park HS, Chae DH, Yu A, Park JH, Heo J, Cho K, Kim J, Lim B, Kim JM, Axelrad JE, Jang KK, Im JP, Koh SJ, Kim BS, Yu KR.   +15 more
europepmc   +1 more source

DUOX2 activation drives bacterial translocation and subclinical inflammation in IBD-associated dysbiosis. [PDF]

Gut
Hazime H, Ducasa GM, Santander AM, Brito N, Gonzalez-Horta EE, Quintero MA, Barnes S, Wilson L, Zhang Y, Yu F, Gharaibeh RZ, Jobin C, Faust KM, Damas OM, Deshpande A, Kerman DH, Proksell S, Pignac-Kobinger J, Fernández I, Burgueño JF, Abreu MT.   +20 more
europepmc   +1 more source

Sex Differences in Colonic Inflammation are Driven by Epithelial-Specific Expression of Estrogen Receptor Alpha. [PDF]

Gastro Hep Adv
Pereda GA, Kocinski AD, Broncano AV, McNeer SK, Raymond ML, Ziats NP, Breau KA, Burclaff J, Magness ST, Goodman WA.   +9 more
europepmc   +1 more source

A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen. [PDF]

Nat Genet
Di Martino ML, Jenniches L, Bhetwal A, Eriksson J, Lopes ACC, Ntokaki A, Pasqua M, Sundbom M, Skogar M, Graf W, Webb DL, Hellström PM, Mateus A, Barquist L, Sellin ME.   +14 more
europepmc   +1 more source