Results 11 to 20 of about 1,067,070 (316)
Clinical Radiology, 2021 Psychological issues around colorectal cancer (CRC) can emerge from the point CRC is suspected, through treatment, to living with or beyond cancer. One-third of patients report high levels of anxiety while undergoing investigations for suspected cancer, and emotional difficulties, particularly anxiety and fear of recurrence, can persist for years ...
Miles, Anne, Redeker, Claudia
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Nature Reviews Disease Primers, 2015 Colorectal cancer had a low incidence several decades ago. However, it has become a predominant cancer and now accounts for approximately 10% of cancer-related mortality in western countries. The 'rise' of colorectal cancer in developed countries can be attributed to the increasingly ageing population, unfavourable modern dietary habits and an increase
Kuipers, E.J. +7 more
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Organoids and Colorectal Cancer [PDF]
Cancers, 2021 Organoids were first established as a three-dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system to study many human physiological and pathological processes that affect a variety of tissues and organs. In particular, organoids are becoming very useful tools to dissect colorectal cancer (CRC)
Alberto Muñoz +10 more
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Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study [PDF]
Annals of Coloproctology, 2023 Purpose Minimally invasive surgery (MIS) is currently the standard treatment for rectal cancer. However, its limitations include complications and incomplete total mesorectal excision (TME) due to anatomical features and technical difficulties. Transanal
Kiho You +10 more
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Acta Oncologica, 2003 Colorectal cancer (CRC) is one of the leading causes of mortality and accounts for approximately 200000 deaths per year in Europe and the USA. Chemotherapy and radiotherapy have established roles in the treatment of colorectal cancer and can contribute to cure rate, prolongation of survival, reduction of local rates of recurrence and enhanced quality ...
Nicum, S, Midgley, R, Kerr, D
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Radiogenomics in Colorectal Cancer [PDF]
Cancers, 2021 The steady improvement of high-throughput technologies greatly facilitates the implementation of personalized precision medicine. Characterization of tumor heterogeneity through image-derived features—radiomics and genetic profile modifications—genomics, is a rapidly evolving field known as radiogenomics.
Badic, Bogdan +4 more
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Low Expression of DYRK2 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 2) Correlates with Poor Prognosis in Colorectal Cancer. [PDF]
, 2016 Dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2) is a member of dual-specificity kinase family, which could phosphorylate both Ser/Thr and Tyr substrates. The role of DYRK2 in human cancer remains controversial.
Chu, Zhonghua +7 more
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Mayo Clinic Proceedings, 2007 Cancers of the colon and rectum will affect 1 in 17 North Americans during their lifetime. The progress witnessed in the treatment of these cancers in recent years has been remarkable. Improvements have been realized in surgical technique, radiation therapy, and systemic therapies, particularly with the addition of oxaliplatin and irinotecan to the ...
Sharlene, Gill +2 more
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Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression
Journal of Translational Medicine, 2022 Background Colorectal cancer (CRC) is one of the lethal cancers with a high mortality rate worldwide and understanding the mechanisms behind its progression is critical for improving patients’ prognosis and developing therapeutics.
Yu Liu +10 more
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Colorectal Cancer Screening [PDF]
Gastroenterology Research and Practice, 2012 Colorectal cancer (CRC) is the most common malignancy worldwide if men and women are considered together, with more than 1,200,000 new cases per year. The highest incidence rates are found in Australia and New Zealand, Europe, and North America. In addition, it represents, after lung cancer, the second leading cause of cancer-related death among these ...
Quintero, E +3 more
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