Results 251 to 260 of about 5,673,125 (350)

Metformin's multifaceted role in colorectal cancer: mechanisms of action and synergy with standard treatments. [PDF]

Discov Oncol
Kolour HR, Bahrami N, Nazemalhosseini-Mojarad E, Sadeghi A, Shamsara M, Fatemi N.   +5 more
europepmc   +1 more source

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

Advanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu, Liting Huang, Suzhen Bi, WeiKaixin Kong, Wanting Feng, Yingjia Li, Zhengwei Xie, Peipei Shan, Sujie Zhu   +8 more
wiley   +1 more source

Colorectal cancer in a man with silver-Russell syndrome: a case report. [PDF]

Oxf Med Case Reports
Ibraik F, Hammouri I, Arafat H, Hammouri AG, Qahoush H.   +4 more
europepmc   +1 more source

Prevention and Treatment of Colorectal Cancer by Natural Agents from Mother Nature

, 2013
Bharat B. Aggarwal, Sahdeo Prasad, Bokyung Sung, Sunil Krishnan, Sushovan Guha   +4 more
openalex   +2 more sources

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

Sarcopenia in Colorectal Cancer Surgery-Minimally Invasive vs. Open. [PDF]

J Cachexia Sarcopenia Muscle
Merboth F, Müller-Oerlinghausen M, Nebelung H, Bogner A, Pecqueux M, Salisch N, Distler M, Plodeck V, Hoffmann RT, Fritzmann J, Weitz J, Kirchberg J.   +11 more
europepmc   +1 more source

Supplementary Table S5 from Associations between Dietary Patterns and Incident Colorectal Cancer in 114,443 Individuals from the UK Biobank: A Prospective Cohort Study

Samuel L. Skulsky, Dimitrios A. Koutoukidis, Jennifer Carter, Carmen Piernas, Susan A. Jebb, Min Gao, Nerys M. Astbury   +6 more
openalex   +1 more source

GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation

Advanced Science, EarlyView.
Schematic diagram of the mechanism by which GSK461364 inhibits NLRP3 inflammasome activation. GSK461364 inhibits the phosphorylation of NEK7 likely at serine 221 and serine 260 by suppressing the activity of PLK1, thereby restraining the formation of the NLRP3 inflammasome.
Ruiheng Luo, Mingliang Ma, Dan Wang, Ling Luo, Xueming Xu, Lingmin Huang, Fupeng Wang, Guangyan Kuang, Huiqi Liu, Rui Ni, Xin Li, Qinghua Zhang, Shengfeng Wang, Kai Zhao   +13 more
wiley   +1 more source

Expression and Clinical Significance of Sideroflexin 4 (SFXN4) in Colorectal Cancer. [PDF]

In Vivo
Shamoun L, Dimberg J, Geijerstam KAF, Moltubak E, Landerholm K, Wågsäter D.   +5 more
europepmc   +1 more source

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang, Yuanhao Zhou, Qingyuan Wu, Yishu Li, Yilin Huang, Kexin Yu, Ping Li, Zhenye Lv, Haotian Liu, Hai Zou, Huiyu Liu, Xiaozhou Mou   +11 more
wiley   +1 more source