Results 211 to 220 of about 3,050,618 (255)

Low-energy spontaneous fabrication of quercetin-loaded orange oil nanoemulsion for induction of colorectal cancer cell apoptosis. [PDF]

BMC Complement Med Ther
Abd-Rabou AA, Edris AE.
europepmc   +1 more source

Novel Triazole-Diquinothiazine Hybrids Modulating Apoptosis and Stress Pathways in Colorectal Cancer Cells. [PDF]

Pharmaceuticals (Basel)
Giercuszkiewicz-Haśnik K, Skonieczna M, Morak-Młodawska B, Jeleń M.   +3 more
europepmc   +1 more source

Epigenetic Activation of the KDM6B-DKK1 Axis Promotes Colorectal Cancer Peritoneal Metastasis Through Wnt/β-Catenin-Associated EMT. [PDF]

J Cell Mol Med
Zhai Z, Chen J, Yang Y, Li M.
europepmc   +1 more source

RETRACTION: USP44 Suppresses Proliferation and Enhances Apoptosis in Colorectal Cancer Cells by Inactivating the Wnt/β-catenin Pathway via Axin1 Deubiquitination. [PDF]

Cell Biol Int
europepmc   +1 more source

Correction to "[NSUN2 promotes colorectal cancer progression and increases lapatinib sensitivity by enhancing CUL4B/ErbB-STAT3 signalling in a non-m5C manner]". [PDF]

Clin Transl Med
europepmc   +1 more source

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Effect of TNIK upregulation on JQ1-resistant human colorectal cancer HCT116 cells

Biochemical and Biophysical Research Communications, 2020
JQ1 disrupts the binding of bromodomain and extra-terminal (BET) family of proteins to acetylated histones, modulates the expression of various genes, and inhibits the proliferation of cancer cells. We established two JQ1-resistant sublines from human colorectal cancer HCT116 cells. These resistant cells showed an 8- to 9-fold higher resistance to JQ1,
Chihiro Takahashi, Shingo Kondo, Kensuke Sadaoka, Shuhei Ishizuka, Kohji Noguchi, Yu Kato, Yoshikazu Sugimoto   +6 more
openaire   +2 more sources

Significance of Notch and Wnt signaling for chemoresistance of colorectal cancer cells HCT116

Journal of Cellular Biochemistry, 2018
Abstract5‐fluorouracil (5‐FU) and oxaliplatin (OxaPt) are the main chemotherapeutics for colorectal cancer (CRC). Chemotherapy response rates for advanced CRC remain low, primarily due to intrinsic or acquired chemoresistance. The importance of Notch and Wnt signaling for carcinogenesis of CRC as well as crosstalk of Notch and Wnt signaling with many ...
Egle Kukcinaviciute, Violeta Jonusiene, Ausra Sasnauskiene, Daiva Dabkeviciene, Eigile Eidenaite, Arvydas Laurinavicius   +5 more
openaire   +2 more sources

DIFFERENTIAL GROWTH INHIBITION AND INDUCTION OF APOPTOSIS BY GOSSYPOL BETWEEN HCT116 AND HCT116/BAX^−/– COLORECTAL CANCER CELLS

Clinical and Experimental Pharmacology and Physiology, 2007
SUMMARY Bax is a very important pro‐apoptosis molecule. HCT116/Bax−/– cells do not express the pro‐apoptosis Bcl‐2 family member, Bax. In the present study, the anticancer effects of gossypol on HCT116 and HCT116/Bax−/– cells were compared in terms of inhibition of cell growth, inhibition of colony formation and induction of apoptosis.
Manchao, Zhang, Hongpeng, Liu, Zhenkun, Tian, Jenny, Huang, Mylene, Remo, Q Quentin, Li   +5 more
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Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells

Journal of Natural Products, 2018
HCT116 colorectal cancer cell sensitivity to peloruside A (PLA) in normoxia is not altered by hypoxia preconditioning of the cells. We examined whether the PLA effects were altered in hypoxia and whether the activity was dependent on p53. The cytotoxicity of PLA in wild-type HCT116 cells was largely unaffected by hypoxia; however, cells in which p53 ...
Jiří Řehulka, Narendran Annadurai, Ivo Frydrych, Petr Džubák, John H. Miller, Marián Hajdúch, Viswanath Das   +6 more
openaire   +3 more sources