Results 201 to 210 of about 33,936 (220)

Bidirectional Signals Transduced by TOPK-ERK Interaction Increase Tumorigenesis of HCT116 Colorectal Cancer Cells

Gastroenterology, 2007
Aberrant activation of Ras and Raf in mitogen-activated protein kinase (MAPK) signaling has been linked with cancer. However, the role of MAPK kinases (MAPKKs or MEKs) in cancer is unclear, although constitutively activated MEK1, which does not exist in nature, is "oncogenic." Herein, we found that T-cell-originated protein kinase (TOPK), a member of ...
Feng, Zhu, Tatyana A, Zykova, Bong Seok, Kang, Zhe, Wang, Mara C, Ebeling, Yasuhito, Abe, Wei-Ya, Ma, Ann M, Bode, Zigang, Dong   +8 more
openaire   +2 more sources

Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil

International Journal of Oncology, 2004
5-Fluorouracil (5-FU) is the chemotherapeutic drug of choice for the treatment of metastatic colorectal cancer, but resistance to 5-FU remains a major obstacle to successful therapy. We generated 5-FU-resistant derivatives of the HCT116 human colon cancer cell line by serial passage of these cells in the presence of increasing 5-FU concentrations in an
Paula M, de Angelis, Bjørg, Fjell, Katherine L, Kravik, Terje, Haug, Siv H, Tunheim, Wenche, Reichelt, Marzieh, Beigi, Ole Petter, Clausen, Eivind, Galteland, Trond, Stokke   +9 more
openaire   +2 more sources

Colorectal cancer statistics, 2023

Ca-A Cancer Journal for Clinicians, 2023
Rebecca L Siegel, Nikita Sandeep Wagle, Andrea Cercek   +2 more
exaly  

Clinical management of metastatic colorectal cancer in the era of precision medicine

Ca-A Cancer Journal for Clinicians, 2022
Fortunato Ciardiello, Davide Ciardiello, Giulia Martini   +2 more
exaly  

Assessing effects of caffeic acid on cytotoxicity, apoptosis, invasion, GST enzyme activity, oxidant, antioxidant status and micro-RNA expressions in HCT116 colorectal cancer cells

South African Journal of Botany, 2023
Mucahit Seçme, Dogukan Mutlu, Levent Elmas   +2 more
exaly  

Cancer statistics for A merican I ndian and A laska N ative individuals, 2022: Including increasing disparities in early onset colorectal cancer

Ca-A Cancer Journal for Clinicians, 2023
Tyler B Kratzer, Ahmedin Jemal, Kimberly D Miller   +2 more
exaly  

Mailed fecal immunochemical test outreach for colorectal cancer screening: Summary of a Centers for Disease Control and Prevention–sponsored Summit

Ca-A Cancer Journal for Clinicians, 2020
Samir Gupta, Gloria D Coronado, Keith Argenbright   +2 more
exaly  

OP54 EFFECT OF HIGH GLUCOSE ON GENE EXPRESSION IN HCT116 COLORECTAL CANCER CELLS

Diabetes Research and Clinical Practice, 2014
H.M. Lee, S.C. Lee, W.C.Y. Leung, L. He, R.C.W. Ma, A.P.S. Kong, J.C.N. Chan   +6 more
openaire   +1 more source

American Cancer Society Colorectal Cancer Survivorship Care Guidelines

Ca-A Cancer Journal for Clinicians, 2015
Khaled El-Shami, Anne Willis, Johnie Rose   +2 more
exaly  

Recent progress in Lynch syndrome and other familial colorectal cancer syndromes

Ca-A Cancer Journal for Clinicians, 2018
Patrick M Boland, Matthew B Yurgelun, C Richard Boland   +2 more
exaly