PDT-regulated immune gene prognostic model reveals tumor microenvironment in colorectal cancer liver metastases. [PDF]
Xu J +6 more
europepmc +1 more source
Bevacizumab added to systemic chemotherapy remains a cornerstone of metastatic colorectal cancer treatment, but its effectiveness is variable. Tumors can bypass the VEGF blockade by activating other pro‐angiogenic pathways, hampering the identification of predictive biomarkers.
Büsra Akay Hacan +9 more
wiley +1 more source
Enhancer RNAs profiling in colorectal cancer liver metastases reveals novel molecular subtypes with prognostic and therapeutic relevance. [PDF]
Bu X +6 more
europepmc +1 more source
Abstract Objective Up to 14% of women with early‐stage endometrial carcinoma (EEC) are diagnosed before menopause. Although ovarian preservation (OP) within surgical staging might avoid surgical menopause, its rate remains low in clinical practice, probably because the impact of OP on survival outcomes is unclear.
Antonio Raffone +12 more
wiley +1 more source
Chemotherapy of colorectal cancer liver metastases
openaire +1 more source
Reduced Floxuridine Dose Limits Hepatobiliary Toxicity Without Negatively Impacting Survival After Resection of Colorectal Cancer Liver Metastases. [PDF]
Labadie KP +11 more
europepmc +1 more source
Comments on "Differential prognostic impact of liver resection by the site of concurrent extrahepatic diseases in patients with colorectal cancer liver metastases: a nationwide multicenter study". [PDF]
Abulaiti A, Tuergan T, Aji T.
europepmc +1 more source
Closing the Loop in Precision Oncology: A Digital Twin‐Driven Paradigm for Dynamic Decision‐Making
This review introduces the Closed‐Loop Intelligent Oncology System (CIOS), a five‐layer framework integrating digital twins and AI to enable adaptive, data‐driven cancer treatment. By synthesizing advances in multimodal perception, mechanistic simulation, and safe reinforcement learning, CIOS charts a roadmap toward dynamic, personalized oncology ...
Junye Zhu +3 more
wiley +1 more source
A machine learning-based prognostic stratification of locoregional interventional therapies for patients with colorectal cancer liver metastases: a real-world study. [PDF]
Wang J +12 more
europepmc +1 more source

