Utilizing imaging features of preoperative gadoxetic acid-enhanced MRI for predicting lymphovascular invasion in colorectal cancer liver metastases and exploring its impact on survival. [PDF]
Xing Q, Cui Y, Gu XL, Li XT, Sun YS.
europepmc +1 more source
Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue +6 more
wiley +1 more source
<sup>18</sup>F-FDG PET radiomics model for predicting TARE response in patients with colorectal cancer liver metastases. [PDF]
Topcuoglu OM +5 more
europepmc +1 more source
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer +2 more
wiley +1 more source
High levels of serum cholesterol increase the risk of developing vessel co-opting tumors in colorectal cancer liver metastases. [PDF]
Gantz A +9 more
europepmc +1 more source
Physical Activity and Risk of Liver Cancer: A Competing Risk Analysis
ABSTRACT Physical activity is associated with lower risk of liver cancer, but obtaining an unbiased estimate of the causal effect is challenging due to the competing risk of death due to any other cause. We performed a causal competing risk analysis to estimate the total effect of physical activity on risk of liver cancer in the presence of competing ...
Frances E. M. Albers +9 more
wiley +1 more source
Predicting early recurrence of colorectal cancer liver metastases: an integrative approach using radiomics and machine learning. [PDF]
Lin Y, Huang Y, Liu Z, Feng X, Yang C.
europepmc +1 more source
Activity of Low Dose Nivolumab in Patients With Advanced Squamous Cell Carcinomas and Other Cancers
ABSTRACT Immune checkpoint inhibitors such as anti–PD‐1 antibodies are essential in cancer therapy. Emerging data suggest that lower doses may be effective and more economical, though further evidence is needed. We conducted a retrospective study at Centre Léon Bérard to assess the efficacy and safety of low‐dose nivolumab (20 mg every 3 weeks) in ...
Thibault Gauduchon +16 more
wiley +1 more source
ABSTRACT Twenty‐five percent of colon cancer patients having curative surgery will recur. Most of them will die from distant metastasis partly due to shortcomings of routine histopathological analysis, that is, undetected tumor cells in the regional lymph node field.
Basel Sitohy +20 more
wiley +1 more source
Delta-Radiomics Biomarker in Colorectal Cancer Liver Metastases Treated with Cetuximab Plus Avelumab (CAVE Trial). [PDF]
Nardone V +14 more
europepmc +1 more source

