Results 231 to 240 of about 4,157,974 (295)

Immune‐Related Prognostic Gene Identification in Lung Squamous Cell Carcinoma With the Cancer Genome Atlas Mining and Immunohistochemistry Validation

iNew Medicine, EarlyView.
ABSTRACT Objective In the cancer microenvironment, stromal and immune cells hold clinical importance. In lung squamous cell carcinoma (LSCC), the aim of this study was to find immune‐linked gene expression that has prognostic pertinence. Methods From the Cancer Genome Atlas, this study obtained the LSCC gene expression profile.
Weijia Jiang, Jing Xu, Wenwen Ma, Qingjie Zhu, Pawin Pongkorpsakol, Guoping Sun   +5 more
wiley   +1 more source

Repeat ablation and single-session ablation in patients with multiple colorectal cancer liver metastases after chemotherapy failure. [PDF]

World J Gastroenterol
Gao SQ, Zhang BW, Zhao QY, Jiang TA.
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Differential prognostic impact of liver resection by the site of concurrent extrahepatic diseases in patients with colorectal cancer liver metastases: a nationwide multicenter study (correspondence). [PDF]

Int J Surg
Yu Y, Zhong N, Wang BL.
europepmc   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

Interdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh, Manjeet Kumar, Kajal Kamra   +2 more
wiley   +1 more source

"Winning" with laparoscopic liver resection for colorectal cancer liver metastases (CRLM). [PDF]

Hepatobiliary Surg Nutr
Schmitz R, Tohme ST, Geller DA.
europepmc   +1 more source

Chemotherapy of colorectal cancer liver metastases

European Journal of Cancer Supplements, 2003
openaire   +1 more source

Characteristics of ascitic fluid and diagnosis of bacterial peritonitis in malignant ascites: An observational study

Journal of Hospital Medicine, EarlyView.
Abstract Background Bacterial peritonitis in patients with malignant ascites (BP‐MA) is an understudied, high‐mortality condition. While ascitic polymorphonuclear (PMN) cell count ≥ 250 cells/mm3 defines the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis, an ascitic fluid parameter for the diagnosis of BP‐MA has not ...
Mark M. Kelly, Nicole Johnston, Joanne Kuznicki, Stacy A. Johnson, Hannah Imlay   +4 more
wiley   +1 more source

Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Ascelia‐Manganese‐Based MRI Contrast Agent (ACE‐MBCA) in Adult Subjects With and Without Hepatic Impairment

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Orally administered Ascelia‐manganese‐based contrast agent (ACE‐MBCA) is used for liver MRI, but its feasibility in patients with hepatic dysfunction remains unknown. Purpose To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of ACE‐MBCA in subjects without/with hepatic impairment.
Amit G. Singal, Eric Lawitz, Andreas Norlin, Nadilka Hettiarachchige, Thomas Bengtsson, Bachir Taouli   +5 more
wiley   +1 more source

ASO Author Reflections: Optimizing the Dose of Floxuridine for the Adjuvant Treatment of Resected Colorectal Cancer Liver Metastases. [PDF]

Ann Surg Oncol
Labadie KP, Melstrom LG.
europepmc   +1 more source