Results 221 to 230 of about 4,157,974 (295)

Cancer in Seychelles: A Population‐Based Study on Incidence, Trends and Stage at Diagnosis (2005–2024)

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Seychelles, the smallest country in Africa but with the highest GDP per capita, has experienced rapid socioeconomic development. We analysed 20‐year cancer incidence trends (2005–2024) using data from the Seychelles National Cancer Registry (SNCR).
Anne Finesse   +5 more
wiley   +1 more source

Cancer in the Oldest‐Old in Super‐Aging Japan: Trends and Characteristics From National Registry Data

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Globally, Japan has the largest proportion of individuals aged ≥ 85 years. However, epidemiological studies on cancer in this age group are limited. This study aimed to investigate cancer trends and characteristics among the oldest‐old adults (aged ≥ 85 years) in Japan, using population‐based national and prefectural cancer registry data on ...
Sayo Tanaka   +2 more
wiley   +1 more source

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer   +20 more
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

open access: yesiMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding   +9 more
wiley   +1 more source

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