Results 11 to 20 of about 4,253,992 (294)
Multilevel Heterogeneity of Colorectal Cancer Liver Metastasis
Cancers, 2023 Colorectal cancer liver metastasis (CRLM) is a highly heterogeneous disease. Therapies that target both primary foci and liver metastasis are severely lacking. Therefore, understanding the features of metastatic tumor cells in the liver is valuable for the overall control of CRLM patients.
Hao Chen +5 more
openaire +3 more sources
Emerging mechanisms progress of colorectal cancer liver metastasis [PDF]
Frontiers in Endocrinology, 2022 Colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer-related mortality worldwide. A total of 20% of CRC patients present with distant metastasis. The hepatic portal venous system, responsible for collecting most intestinal blood, makes the liver the most common site of CRC metastasis.
Wenhu Zhao +6 more
openaire +4 more sources
Radiomics and Radiogenomics in Evaluation of Colorectal Cancer Liver Metastasis [PDF]
Frontiers in Oncology, 2022 Colorectal cancer is one common digestive malignancy, and the most common approach of blood metastasis of colorectal cancer is through the portal vein system to the liver.
Yun Wang +3 more
doaj +3 more sources
Current OncologyColorectal cancer is one of the most common malignancies worldwide, with liver metastasis being one of its primary metastatic patterns and a significant cause of death.
Dandan Cao, Aiping Zhou
doaj +2 more sources
Immune mediated and direct killing of colorectal cancer by reovirus [PDF]
, 2012 Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease.
Adair, Robert Allan
core +5 more sources
Identificació de nous marcadors moleculars en metàstasi hepàtica de càncer colorectal [PDF]
, 2010 [cat] L’objectiu d’aquest treball és la identificació i caracterització de les principals alteracions en metàstasi hepàtica (MH) de càncer colorectal (CCR) tant a nivell d’expressió gènica com de metilació de l’ADN.
Padullés Mosella, Laura
core +6 more sources
Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer [PDF]
Cancers, 2020 The liver is the dominant site of metastasis for patients with colorectal cancer. For those with isolated liver metastases, surgical resection with systemic therapy has led to long-term remission in as high as 80% of patients in well-selected cohorts. This review will focus on how systemic therapy should be integrated with resection of liver metastases;
Gloria Chan, Cheng E. Chee
openaire +2 more sources
The role of the immunoescape in colorectal cancer liver metastasis
PLOS ONE, 2021 The expression of programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) indicate the efficacy of anti-PD-1/PD-L1 therapy in colorectal cancer (CRC), but are less useful for monitoring the efficacy of therapy of CRC liver metastasis (CRLM).
Chie Takasu +8 more
openaire +5 more sources
microRNA biomarkers in colorectal cancer liver metastasis [PDF]
Journal of Cancer, 2018 Liver metastasis is a primary factor of prognosis and long-term survival for patients diagnosed with colorectal cancer (CRC). Colorectal cancer liver metastasis (CRCLM), is a complex biological process involving multiple factors and steps, and its mechanisms are yet to be discovered.
Huang, Shulin +5 more
openaire +2 more sources
Liver immune microenvironment and metastasis from colorectal cancer-pathogenesis and therapeutic perspectives [PDF]
, 2021 A drastic difference exists between the 5-year survival rates of colorectal cancer patients with localized cancer and distal organ metastasis. The liver is the most favorable organ for cancer metastases from the colorectum.
Ward, Simon E. +11 more
core +2 more sources