Results 31 to 40 of about 4,253,992 (294)

Analysis of Colorectal Cancers with Liver Metastasis.

Nippon Daicho Komonbyo Gakkai Zasshi, 1993
大腸癌肝転移症例において肝転移巣に対し種々の治療を試み,その効果について検討した.1980年～1991年の12年間に当教室で経験した大腸癌肝転移症例は91例(同時性78例,異時性13例)で,これらに対する治療のうちわけは,リザーバーの留置による動注化学療法17例,動脈塞栓術(TAE)3例,肝切除術14例,大腸原発巣のみ切除し全身化学療法を併用したもの52例,試験開腹術5例であった.H1症例に対しては肝切除術はきわめて有効な手段であると考えられた.また肝切除術の対象とならないH3症例に対しては,リザーバーを設置しての間歇的反復動注化学療法(Epi-ADR 30mg,MMC 4mgを交互に1回/週)は全身化学療法より肝転移巣に対しての直接効果が高く有効な治療法と考えられ,また術後のlife ...
H. Kawahara, K. Hirai, K. Ashikaga, Y. Yamada, T. Kimura, H. Kuroda, K. Sato, T. Aoki   +7 more
openaire   +3 more sources

The Roles of Carcinoembryonic Antigen in Liver Metastasis and Therapeutic Approaches

Gastroenterology Research and Practice, 2017
Metastasis is a highly complicated and sequential process in which primary cancer spreads to secondary organic sites. Liver is a well-known metastatic organ from colorectal cancer.
Joo Han Lee, Seong-Wook Lee
doaj   +1 more source

Echinococcal hepatic lesion mimicking metastasis from colon cancer: two case reports

BMC Surgery, 2021
Background Echinococcus is a worldwide zoonosis, primarily causing liver lesions. Accidentally detected, these lesions enter the differential diagnosis of a tumor, including metastasis. This situation is especially challenging in patients with colorectal
Marionna Cathomas, Paolo Abitabile, Rok Dolanc, Christine Glaser, Gieri Cathomas   +4 more
doaj   +1 more source

Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern [PDF]

, 2021
: Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that Claudin-2 is functionally required for colorectal cancer liver metastasis and that Claudin-2 expression in primary colorectal ...
Vermeulen, Peter, Siegel, Peter M., Siegel, Peter M, Annis, Matthew G., Johnson, Radia M, Gao, Zu-Hua, Grünhagen, Dirk J; id_orcid, Chabot, Jaclyn, van Laere, Steven, Lazaris, Anthoula, Hachem, Yasmina, Petrillo, Stephanie K, Altinel, Gulbeyaz, Yumeen, Sara, Huxham, Jennifer, Verhoef, Cornelis, Metrakos, Peter, Yu, Alan S.L., Yu, Alan S L, Petrillo, Stephanie K., Palmieri, Vincent, Tabaries, Sebastien, Abdellatif, Amri, Annis, Matthew G, Meti, Nicholas, Omeroglu, Atilla, Johnson, Radia M., Grunhagen, Dirk J., Peter Vermeulen, Peter Metrakos, Zu-Hua Gao, Sébastien Tabariès, Jaclyn Chabot, Radia M. Johnson, Stephanie K. Petrillo, Matthew G. Annis, Amri Abdellatif, Anthoula Lazaris, Cornelis Verhoef, Dirk J. Grünhagen, Vincent Palmieri, Nicholas Meti, Alan S. L. Yu, Jennifer Huxham, Steven Van Laere, Yasmina Hachem, Gulbeyaz Altinel, Sara Yumeen, Peter M. Siegel, Atilla Omeroglu   +49 more
core   +1 more source

Advances in the mechanism and treatment strategy of colorectal cancer lung metastasis

结直肠肛门外科, 2023
The incidence of colorectal cancer has been increasing year by year, and its mortality rate ranks among the top five for cancer diseases. Distant metastasis and recurrence are major factors that affect the prognosis of colorectal cancer patients, with ...
Xu Guohui, Ma Dening
doaj   +1 more source

Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis

Neoplasia: An International Journal for Oncology Research
Background: Liver metastasis is a leading cause of colorectal cancer mortality. Therefore, the underlying mechanism and potential therapeutic target of colorectal cancer liver metastasis urge to be found.
Jing Chen, Shenghua Zhang, Xinmei Huang, Qianqian Wang, Weiyan Xu, Jing Huang, Yuming Su, Qinkun Sun, Xiaojuan Du, Baocai Xing, Xiaoyan Qiu   +10 more
doaj   +1 more source

Construction and Evaluation of Metastatic Risk Model in Left and Right Colorectal Cancer

Zhongliu Fangzhi Yanjiu, 2022
Objective To identify the influence factors and construct a predicted model for liver, lung, bone, or brain metastasis among patients with left or right colorectal cancer. Methods Patients with colorectal cancer with information on liver, lung, bone, and
GE Yizhi, XU Yan, CHEN Xiaojun, GU Xiang
doaj   +1 more source

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]

, 2012
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Prem Kumar, Sutherland K Maciver, Manuel Salto-tellez, Celestial T. Yap (142210), Tochhawng, L., Zhuo, J., Celestial T Yap, Maciver, S.K., Koh, Shiuan, K. Maciver, Salto-Tellez Manuel, Manikandan Jayapal (64624), Tan, Ee Hong, Hooi, S., Jayapal, Manikandan, Maciver, Sutherland K., Yaw Chyn Lim (142208), Zhuo Jingli, Lalchhandami Tochhawng (142188), Jingli Zhuo, Ee Hong Tan (142182), Ee Hong Tan, Alan Prem Kumar (142201), Tay Hwee Kee, Lim, Yaw Chyn, Tay, H., Kumar, A.P., Tochhawng, Lalchhandami, Alan Prem Kumar, Maciver, Sutherland K, Ami Tochhawng, Koh, S., Salto-Tellez, M., Hwee Kee Tay (64625), Tay, H.K., Maciver, S., Benedict Yan (142185), Yap Celestial T., Kumar, Alan Prem, Shiuan Koh (142191), Lalchhandami Tochhawng, Lim, Y., Shing Chuan Hooi (50996), Jayapal Manikandan, Goh, Yaw Chong, Shiuan Koh, Tan, E.H., Yap, C., Yap, Celestial T, Yap, Celestial T., Tochhawng Lalchhandami, Tan, E., Lim, Y.C., Hooi, Shing Chuan, An Jayapal, Yan, B., Hwee Kee Tay, Hooi, S.C., Kumar Alan Prem, Sutherland K. Maciver (142194), Tan Ee Hong, Celestial T. Yap, Goh, Y., Manikandan Jayapal, Maciver Sutherland K., Goh Yaw Chong, Jingli Zhuo (142178), Zhuo, Jingli, Yap, C.T., Benedict Yan, Lim Yaw Chyn, Yan, Benedict, Jayapal, M., Yaw Chyn Lim, Goh, Y.C., Salto-Tellez, Manuel, Yaw Chong Goh, Yaw Chong Goh (142205), Koh Shiuan, Yan Benedict, Hooi Shing Chuan, Manuel Salto-Tellez (142198), Tay, Hwee Kee, Shing Chuan Hooi   +83 more
core   +2 more sources

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis [PDF]

, 2021
Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can effectively prevent liver metastasis.
Hu, M, Dayton, P.A, Li, L, Rojas, J.D, Wang, A.Z, Sendi, H, Wang, J, Yazdimamaghani, M, Graboski, A, Moody, A.S, Huang, L, Sultanpuram, N, McCabe, E, Zhang, J   +13 more
core   +1 more source

Predictive Value of Immune Inflammation Combined with Liver Function Hematological Indicators for Metastasis of Colorectal Cancer

Zhongliu Fangzhi Yanjiu
ObjectiveTo explore the predictive value of immune inflammation combined with liver function hematological indicators for the metastasis of colorectal cancer.
Xuelei CHU, Chen AN, Lingze XI, Hongting XIE, Mingtong ZONG, Peng XUE, Shijie ZHU   +6 more
doaj   +1 more source