Results 51 to 60 of about 141,334 (303)

Long term outcomes of simultaneous laparoscopic versus open resection for colorectal cancer with synchronous liver metastases

Asian Journal of Surgery, 2019
Summary: Background/Objective: Because of the advancements in the surgical techniques of liver resection and improvements in anesthesia and postoperative critical care, the simultaneous resection of synchronous colorectal cancer with liver metastasis ...
Ying-Wei Chen, Ming-Te Huang, Tung-Cheng Chang   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Immune mediated and direct killing of colorectal cancer by reovirus [PDF]

, 2012
Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease.
Adair, Robert Allan
core  

Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer : a multicentre prospective randomized trial

, 2009
Background The effect of additional treatment strategies with antineoplastic agents on intraperitoneal tumor stimulating interleukin levels are unclear.
Willems Wilhelm, Scheele, Johannes, Gutt, Carsten Nils, Jacobi, Christoph A., Scheele Johannes, Menenakos Charalambos, Müller, Joachim M., Mueller Joachim M, Menenakos, Charalambos, Braumann Chris, Jacobi Christoph A, Willems, Wilhelm, Gutt Carsten N, Braumann, Chris   +13 more
core   +1 more source

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis

, 2021
Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can effectively prevent liver metastasis.
Hu, M, Dayton, P.A, Li, L, Rojas, J.D, Wang, A.Z, Sendi, H, Wang, J, Yazdimamaghani, M, Graboski, A, Moody, A.S, Huang, L, Sultanpuram, N, McCabe, E, Zhang, J   +13 more
core   +1 more source

The E3 Ligase NEDD4L Prevents Colorectal Cancer Liver Metastasis via Degradation of PRMT5 to Inhibit the AKT/mTOR Signaling Pathway

Advanced Science
Colorectal cancer is the second most common cause of cancer mortality worldwide, and liver metastasis is the major cause of death of patients with colorectal cancer.
Zhewen Dong, Xiaofei She, Junxian Ma, Qian Chen, Yaqun Gao, Ruiyan Chen, Huanlong Qin, Bing Shen, Hua Gao   +8 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Irreversible electroporation for colorectal cancer liver metastasis: a review

International Journal of Hyperthermia, 2022
Irreversible electroporation (IRE) ablation is gaining popularity over the last decade as a nonthermal alternative to thermal ablation technologies such as radiofrequency ablation (RFA) and Microwave ablation (MWA). This review serves as a practical guide for applying IRE to colorectal cancer liver metastases (CRLM) for interventional radiologists ...
Yilun Koethe, Nicole Wilson, Govindarajan Narayanan   +2 more
openaire   +3 more sources

sFAS/sFASL and sMMP-7: New soluble markers of prognosis and response to therapy in advanced colorectal cancer [PDF]

, 2007
[cat] 1 INTRODUCCIÓN El cáncer colorrectal (CCR) es la tercera causa de diagnóstico de cáncer en todo el mundo. El 11-27% de pacientes se diagnostican en estadio avanzado o metastático.
Nadal Sanmartin, Cristina
core  

Identifying Genetic Mutation Status in Patients with Colorectal Cancer Liver Metastases Using Radiomics-Based Machine-Learning Models

, 2023
For patients with colorectal cancer liver metastases (CRLM), the genetic mutation status is important in treatment selection and prognostication for survival outcomes. This study aims to investigate the relationship between radiomics imaging features and
Janneke van den Bergh, Iris van ‘t Erve, Jaap Stoker, Regina Beets-Tan, Henk Marquering, Remond Fijneman, Irene Nota, Susan van Dieren, Delanie van der Meulen, Rutger-Jan Swijnenburg, Joran Roor, Joost Huiskens, Shira Moos, Nina Wesdorp, Jan Hein van Waesberghe, Cornelis Punt, Geert Kazemier, on behalf of the Dutch Colorectal Cancer Group Liver Expert Panel on behalf of the Dutch Colorectal Cancer Group Liver Expert Panel, Gerrit Meijer, Michiel Zeeuw, Zuhir Bodalal   +20 more
core   +1 more source