Results 91 to 100 of about 252 (108)
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Biomedical Chromatography, 2009
AbstractA rapid and sensitive reversed‐phase high‐performance liquid chromatographic (RP‐HPLC) method was developed to investigate pharmacokinetics of columbianadin, one of the main bioactive constituents in the roots of Angelica pubescens f. biserrata, in rat plasma after intravenous administration to rats at two doses of 10 and 20 mg/kg.
You-Bo, Zhang, Xiu-Wei, Yang
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AbstractA rapid and sensitive reversed‐phase high‐performance liquid chromatographic (RP‐HPLC) method was developed to investigate pharmacokinetics of columbianadin, one of the main bioactive constituents in the roots of Angelica pubescens f. biserrata, in rat plasma after intravenous administration to rats at two doses of 10 and 20 mg/kg.
You-Bo, Zhang, Xiu-Wei, Yang
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Letters in Drug Design and DiscoveryInstrumentation Science & Technology, 2020
The goal of this work was to establish a method to identify and quantify the primary active components in Angelicae pubescentis Radix quickly, simply, and accurately.
Yanmei Feng +5 more
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The goal of this work was to establish a method to identify and quantify the primary active components in Angelicae pubescentis Radix quickly, simply, and accurately.
Yanmei Feng +5 more
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Inflammopharmacology
Ulcerative colitis (UC) is a significant inflammatory bowel disease (IBD) that typically arises from chronic inflammation of the intestinal tract. Report suggest that anti-inflammatory drug plays a crucial role in the protection of UC. The recent study demonstrated that columbianadin has a protective effect against UC induced by dextran sulfate sodium (
Ping Cao
exaly +3 more sources
Ulcerative colitis (UC) is a significant inflammatory bowel disease (IBD) that typically arises from chronic inflammation of the intestinal tract. Report suggest that anti-inflammatory drug plays a crucial role in the protection of UC. The recent study demonstrated that columbianadin has a protective effect against UC induced by dextran sulfate sodium (
Ping Cao
exaly +3 more sources
Journal of Biochemical and Molecular Toxicology
ABSTRACT Background Osteoporosis is a condition in where bones gradually become thin and weak, making them more susceptible to fractures. Columbianadin has showed potential anti‐inflammatory and antioxidant effect.
Songbo Mao, Chuntao Xu, Lin Zou
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ABSTRACT Background Osteoporosis is a condition in where bones gradually become thin and weak, making them more susceptible to fractures. Columbianadin has showed potential anti‐inflammatory and antioxidant effect.
Songbo Mao, Chuntao Xu, Lin Zou
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Phytomedicine
Inhibiting the polarization of microglia toward the M1 pro-inflammatory phenotype to alleviate neuroinflammation and improve neuronal survival is a critical strategy for promoting spinal cord injury (SCI) repair. PTEN, a core regulator of cellular inflammatory responses, exerts its function by negatively modulating the PI3K/AKT signaling pathway ...
Shining Xiao +11 more
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Inhibiting the polarization of microglia toward the M1 pro-inflammatory phenotype to alleviate neuroinflammation and improve neuronal survival is a critical strategy for promoting spinal cord injury (SCI) repair. PTEN, a core regulator of cellular inflammatory responses, exerts its function by negatively modulating the PI3K/AKT signaling pathway ...
Shining Xiao +11 more
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Phytotherapy Research
ABSTRACTAcute myocardial infarction (AMI) is a leading cause of mortality among cardiovascular diseases, yet effective therapies for AMI are limited. Previous studies have suggested cardioprotective effects of columbianadin (CBN), but its specific role in AMI and the underlying mechanisms remain unclear.
Niu Zi‐Chang +8 more
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ABSTRACTAcute myocardial infarction (AMI) is a leading cause of mortality among cardiovascular diseases, yet effective therapies for AMI are limited. Previous studies have suggested cardioprotective effects of columbianadin (CBN), but its specific role in AMI and the underlying mechanisms remain unclear.
Niu Zi‐Chang +8 more
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Identity of Columbianadin and Zosimin
Journal of Pharmaceutical Sciences, 1967T O, Soine, K H, Lee
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Columbianadin: A Novel Coumarin fromHeracleum brunonis
Planta Medica, 1987K S, Khetwal, R P, Pathak
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