Results 111 to 120 of about 303 (129)
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Biomedical Chromatography, 2009
AbstractA rapid and sensitive reversed‐phase high‐performance liquid chromatographic (RP‐HPLC) method was developed to investigate pharmacokinetics of columbianadin, one of the main bioactive constituents in the roots of Angelica pubescens f. biserrata, in rat plasma after intravenous administration to rats at two doses of 10 and 20 mg/kg.
You-Bo, Zhang, Xiu-Wei, Yang
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AbstractA rapid and sensitive reversed‐phase high‐performance liquid chromatographic (RP‐HPLC) method was developed to investigate pharmacokinetics of columbianadin, one of the main bioactive constituents in the roots of Angelica pubescens f. biserrata, in rat plasma after intravenous administration to rats at two doses of 10 and 20 mg/kg.
You-Bo, Zhang, Xiu-Wei, Yang
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Phytomedicine
Over-activation of osteoclastogenesis is a significant factor contributing to bone loss, leading to increased resorption of bone. Columbianadin (CBN), a compound derived from Angelicae Pubescentis Radix, has traditionally been used in Chinese medicine to treat bone-related disorders.
Qiu Wei +8 more
exaly +3 more sources
Over-activation of osteoclastogenesis is a significant factor contributing to bone loss, leading to increased resorption of bone. Columbianadin (CBN), a compound derived from Angelicae Pubescentis Radix, has traditionally been used in Chinese medicine to treat bone-related disorders.
Qiu Wei +8 more
exaly +3 more sources
Instrumentation Science & Technology, 2020
The goal of this work was to establish a method to identify and quantify the primary active components in Angelicae pubescentis Radix quickly, simply, and accurately.
Yanmei Feng +5 more
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The goal of this work was to establish a method to identify and quantify the primary active components in Angelicae pubescentis Radix quickly, simply, and accurately.
Yanmei Feng +5 more
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Journal of Biochemical and Molecular Toxicology
ABSTRACTBackgroundOsteoporosis is a condition in where bones gradually become thin and weak, making them more susceptible to fractures. Columbianadin has showed potential anti‐inflammatory and antioxidant effect. In this experimental study, anti‐osteoporosis effect of Columbianadin against glucocorticoid induced osteoporosis in rats.MethodsIn this ...
Songbo Mao, Chuntao Xu, Lin Zou
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ABSTRACTBackgroundOsteoporosis is a condition in where bones gradually become thin and weak, making them more susceptible to fractures. Columbianadin has showed potential anti‐inflammatory and antioxidant effect. In this experimental study, anti‐osteoporosis effect of Columbianadin against glucocorticoid induced osteoporosis in rats.MethodsIn this ...
Songbo Mao, Chuntao Xu, Lin Zou
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Phytotherapy Research
ABSTRACTAcute myocardial infarction (AMI) is a leading cause of mortality among cardiovascular diseases, yet effective therapies for AMI are limited. Previous studies have suggested cardioprotective effects of columbianadin (CBN), but its specific role in AMI and the underlying mechanisms remain unclear.
Niu Zi‐Chang +8 more
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ABSTRACTAcute myocardial infarction (AMI) is a leading cause of mortality among cardiovascular diseases, yet effective therapies for AMI are limited. Previous studies have suggested cardioprotective effects of columbianadin (CBN), but its specific role in AMI and the underlying mechanisms remain unclear.
Niu Zi‐Chang +8 more
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Inflammopharmacology
Ulcerative colitis (UC) is a significant inflammatory bowel disease (IBD) that typically arises from chronic inflammation of the intestinal tract. Report suggest that anti-inflammatory drug plays a crucial role in the protection of UC. The recent study demonstrated that columbianadin has a protective effect against UC induced by dextran sulfate sodium (
Yanping Zhang +5 more
exaly +3 more sources
Ulcerative colitis (UC) is a significant inflammatory bowel disease (IBD) that typically arises from chronic inflammation of the intestinal tract. Report suggest that anti-inflammatory drug plays a crucial role in the protection of UC. The recent study demonstrated that columbianadin has a protective effect against UC induced by dextran sulfate sodium (
Yanping Zhang +5 more
exaly +3 more sources
Identity of Columbianadin and Zosimin
Journal of Pharmaceutical Sciences, 1967T O, Soine, K H, Lee
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Columbianadin: A Novel Coumarin fromHeracleum brunonis
Planta Medica, 1987K S, Khetwal, R P, Pathak
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