Effects of Nodakenin, Columbianadin, and Umbelliferone Isolated from the Roots of Angelica decursiva on the Gene Expression and Production of MUC5AC Mucin from Human Airway Epithelial NCI-H292 Cells [PDF]
Natural Product Sciences, 2017 Hyun Jae Lee, Choong Jae Lee
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Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023 Background. A major contributor to older disability is osteoarthritis. Radix Angelicae Biseratae (known as Duhuo in China, DH, the dried rhizome of Angelica pubescens) and Dipsaci Radix (known as Xuduan in China, XD, the dried rhizome of Dipsacus asper Wall) herb pair (DXHP) is widely used to treat osteoarthritis, but the underlying molecular ...
Yujiang Xi +12 more
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Journal of Analytical Methods in Chemistry, Volume 2022, Issue 1, 2022., 2022 Qufeng Zhitong capsule (QZC) is a well‐known Chinese patent medicine that has been widely applied for the clinical treatment of rheumatoid arthritis and other inflammatory diseases. To date, its material basis is still unclear, which has greatly limited its clinical application.
Mengjie Xue +6 more
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Pharmacologic Activities of Plant‐Derived Natural Products on Respiratory Diseases and Inflammations
BioMed Research International, Volume 2021, Issue 1, 2021., 2021 Respiratory inflammation is caused by an air‐mediated disease induced by polluted air, smoke, bacteria, and viruses. The COVID‐19 pandemic is also a kind of respiratory disease, induced by a virus causing a serious effect on the lungs, bronchioles, and pharynges that results in oxygen deficiency.
Deepak Timalsina +3 more
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The Use of 1H-qNMR Method for Simultaneous Determination of Osthol, Columbianadin, and Isoimperatorin inAngelicae PubescentisRadix [PDF]
Journal of AOAC INTERNATIONAL, 2020 AbstractObjectiveThe goal of this work was to establish a method to identify and quantify the main active components in Angelicae Pubescentis Radix (APR) quickly, simply, and accurately. This paper reports a novel method which can determine osthol, isoimperatorin, and columbianadin using 1H-qNMR simultaneously and quantitatively.MethodsIn comprehensive
Yanmei Feng +4 more
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Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021 The objective of this work was to provide an economic and practical method for the purification of columbianetin‐β‐D‐glucopyranoside from Angelicae Pubescentis Radix extract. In the static adsorption and desorption, the effects of resin type (D101, HP‐20, AB‐8, GDX‐201, and DA201), contact time (10–360 min), and temperature (298–318 K) were assessed on
Yaqian Zhang +7 more
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Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells [PDF]
Biomolecules & Therapeutics, 2016 Columbianadin (CBN), a natural coumarin from Angelica decursiva (Umbelliferae), is known to have various biological activities including anti-inflammatory and anti-cancer effects. In this study, the anti-proliferative mechanism of actions mediated by CBN was investigated in HCT-116 human colon cancer cells.
Kang, Ji In +3 more
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DataSheet_2_Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice.pdf [PDF]
, 2020 Radix angelicae pubescentis (RAP) has been used in Chinese traditional medicine to treat painful diseases such as rheumatism and headache. A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory ...
Qiuhong Wang (315111) +5 more
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Hepatoprotective and TNF-alpha inhibitory activity of Zosima absinthifolia extracts and coumarins [PDF]
, 2011 Zosima absinthifolia (ZA) extracts and the coumarins (+)-columbianadin and (−)-deltoin were evaluated for their potential hepatoprotective and antiinflamatory effects in a CCl4-induced hepatotoxicity assay in rats and by the inhibition of TNF-α ...
CITOGLU GS +5 more
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The Tissue Distribution of Four Major Coumarins after Oral Administration of Angelicae Pubescentis Radix Extract to Rats Using Ultra-High-Performance Liquid Chromatography. [PDF]
Evid Based Complement Alternat Med, 2019 Angelicae pubescentis radix (APR) is widely applied in treating rheumatoid arthritis in China. Coumarins are the major active compounds of APR extract including columbianetin, columbianetin acetate, osthole, and columbianadin. The in vivo behavior of the four major coumarins of APR has not been systematically reported.
Ge Y +10 more
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