Results 21 to 30 of about 252 (108)

Constructing a Core Collection of the Medicinal Plant Angelica biserrata Using Genetic and Metabolic Data [PDF]

open access: yesFrontiers in Plant Science, 2020
Angelica biserrata is an important medicinal plant in Chinese traditional medicine. Its roots, which are known as Duhuo in Chinese, are broadly applied to treat inflammation, arthritis, and headache. With increasing market demand, the wild resources of A.
Man Liu   +6 more
doaj   +2 more sources

Transport of Twelve Coumarins from Angelicae Pubescentis Radix across a MDCK-pHaMDR Cell Monolayer—An in Vitro Model for Blood-Brain Barrier Permeability

open access: yesMolecules, 2015
Angelicae Pubescentis Radix (APR), a widely used traditional Chinese medicine, is reported to have central nervous system activities. The purpose of this study was to characterize the blood-brain barrier permeability of twelve coumarins from APR ...
Yan-Fang Yang   +4 more
doaj   +2 more sources

Distribution Assessments of Coumarins from Angelicae Pubescentis Radix in Rat Cerebrospinal Fluid and Brain by Liquid Chromatography Tandem Mass Spectrometry Analysis

open access: yesMolecules, 2018
Angelicae Pubescentis Radix (APR) is a widely-used traditional Chinese medicine. Pharmacological studies have begun to probe its biological activities on neurological disorders recently.
Yan-Fang Yang, Lei Zhang, Xiu-Wei Yang
doaj   +2 more sources

Vibrational spectroscopic studies on the natural product, columbianadin

open access: yesSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2003
spectroscop
Nielsen, Ole Faurskov   +4 more
core   +3 more sources

Comparison of Pharmacokinetic Profiles of 14 Major Bioactive Components in Normal and Arthritic Model Rats after Oral Administration of Angelicae pubescentis Radix by UPLC-MS/MS. [PDF]

open access: yesEvid Based Complement Alternat Med, 2022
An ultraperformance liquid chromatography tandem mass spectrometry (UPLC‐MS/MS) method was established to simultaneously determine 14 compounds of Angelicae pubescentis Radix (APR) in normal and arthritis rat plasma in which chloramphenicol and daidzein were used as the internal standards.
Hou A   +8 more
europepmc   +2 more sources

Illumination on Chemical Compounds from Qufeng Zhitong Capsule and Its Potential Pharmacological Mechanism against Rheumatoid Arthritis Based on UHPLC/Q-Orbitrap-MS Combined with Network Pharmacology Analysis. [PDF]

open access: yesInt J Anal Chem, 2022
Qufeng Zhitong capsule (QZC), a Chinese patent medicine officially approved in China for the treatment of rheumatoid arthritis (RA) and other diseases, possesses the primary effects of dispelling wind, relieving pain, and promoting blood circulation, whose clinical applications have been confined owing to the incomplete elucidation of its chemical ...
Xue M   +6 more
europepmc   +2 more sources

Multi-target direct-acting SARS-CoV-2 antivirals against the nucleotide-binding pockets of virus-specific proteins. [PDF]

open access: yesVirology, 2022
The nucleotide-binding pockets (NBPs) in virus-specific proteins have proven to be the most successful antiviral targets for several viral diseases. Functionally important NBPs are found in various structural and non-structural proteins of SARS-CoV-2. In
Rani R   +7 more
europepmc   +2 more sources

Construction of a nanozyme composite drug delivery system based on columbianadin for inflammatory bowel disease therapy. [PDF]

open access: yesRSC Adv
An oral nanozyme-based composite hydrogel (MXene/CBN@GelMA) is developed for targeted inflammatory bowel disease therapy.
Zhang Y   +7 more
europepmc   +3 more sources

Sphondin efficiently blocks HBsAg production and cccDNA transcription through promoting HBx degradation

open access: yesJournal of Medical Virology, Volume 95, Issue 3, March 2023., 2023
Abstract Hepatitis B surface antigen (HBsAg) loss and seroconversion, which is considered as functional cure of chronic Hepatitis B virus (HBV) infection, is rarely achieved even after long‐term antiviral treatments. Therefore, new antiviral strategies interfering with other HBV replication steps are required, especially those that could efficiently ...
Fang Ren   +17 more
wiley   +1 more source

Potential Therapeutic Mechanism of Radix Angelicae Biseratae and Dipsaci Radix Herb Pair against Osteoarthritis: Based on Network Pharmacology and Molecular Docking

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Background. A major contributor to older disability is osteoarthritis. Radix Angelicae Biseratae (known as Duhuo in China, DH, the dried rhizome of Angelica pubescens) and Dipsaci Radix (known as Xuduan in China, XD, the dried rhizome of Dipsacus asper Wall) herb pair (DXHP) is widely used to treat osteoarthritis, but the underlying molecular ...
Yujiang Xi   +12 more
wiley   +1 more source

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