Results 111 to 120 of about 1,090,432 (279)

Did minerals perform prebiotic combinatorial chemistry?

, 1996
Alan W. Schwartz
openalex   +1 more source

Structurally divergent dynamic combinatorial chemistry on racemic mixtures. [PDF]

Nat Commun, 2020
Gianga TM, Pantoș GD.
europepmc   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Combinatorial chemistry and biology: an opportunity for engineers

, 1996
Chaitan Khosla
openalex   +1 more source

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

Challenge of Organic Synthesis-toward the 21st Century. Combinatorial Chemistry.

, 1997
Koichi Fukase
openalex   +2 more sources

Protein-Directed Dynamic Combinatorial Chemistry: An Efficient Strategy in Drug Design. [PDF]

ACS Omega, 2020
Canal-Martín A, Pérez-Fernández R.
europepmc   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Synthesis of New Water-Soluble Metal-Binding Polymers: Combinatorial Chemistry Approach

, 1999
Bruce A. Smith, Rebecca Miller, Mark J. Kurth, Samuel P. Sawan   +3 more
openalex   +2 more sources

Static Combinatorial Chemistry: A High-Pressure Approach to the Synthesis of Macrocyclic Benzoamide Libraries. [PDF]

ACS Comb Sci, 2020
Pikus G, Tyszka-Gumkowska A, Jurczak J.
europepmc   +1 more source