Results 201 to 210 of about 15,411 (236)

High-resolution NMR techniques for solid-phase synthesis and combinatorial chemistry

Drug Discovery Today, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Paul A. Keifer
  +6 more sources

Direct-Injection NMR (DI-NMR):  A Flow NMR Technique for the Analysis of Combinatorial Chemistry Libraries

Journal of Combinatorial Chemistry, 2000
A new tool for analyzing compound libraries by NMR has been developed. Aliquots of solution-state samples (between 120 and 350 microL) are directly injected, using a standard liquids handler, into an NMR (LC-NMR) flow probe. Automated NMR software tracks--and suppresses--intense signals arising from the nondeuterated solvents used (if any) and acquires
Paul A. Keifer, Evan H. Williams, Gabriel Mendez, Stephen H. Smallcombe, Karen E. Salomon, Cathy D. Moore, John L. Belletire   +6 more
openaire   +4 more sources

Analytical Techniques for Combinatorial Chemistry:  Quantitative Infrared Spectroscopic Measurements of Deuterium-Labeled Protecting Groups

Journal of the American Chemical Society, 1996
Infrared microspectroscopy has been developed as a powerful, nondestructive technique for the quantitative analysis of solid-phase, resin-bound chemical reactions. The synthesis and/or application of deuterium isotope containing protecting groups, including acetyl-d3 chloride, benzoyl-d5 chloride, and 2-[[[(tert-butyl-d9)oxy]carbonyl]oximino]-2 ...
Derek C. Cole, Keith Russell, Don E. Pivonka, Mclaren Frances Marie   +3 more
openaire   +3 more sources

Combinatorial chemistry methods for coating development VI. Correlation of high throughput screening methods with conventional measurement techniques

Progress in Organic Coatings, 2003
Abstract Combinatorial chemistry has proven to be a valuable tool for the development of new compounds. In the pharmaceutical industry, where combinatorial chemistry began, the approach has been instrumental in the high-speed development of new drugs.
Radislav A. Potyrailo, Chris Anthony Molaison, Bret Ja Chisholm, Michael Brennan, James N. Cawse, Ronald Eugene Shaffer   +5 more
openaire   +3 more sources

Investigation of Solid-Phase Peptide Synthesis by the Near-Infrared Multispectral Imaging Technique:  A Detection Method for Combinatorial Chemistry

Analytical Chemistry, 1999
A near-infrared (NIR) multispectral imaging spectrometer was used to monitor solid-phase peptide synthesis. This imaging spectrometer has fast scanning ability and high sensitivity because it is based on an acousto-optic tunable filter and a NIR InGaAs focal plane array camera.
Marc Fischer, Chieu D. Tran
openaire   +4 more sources

UZM-13, UZM-17, UZM-19 and UZM-25: synthesis and structure of new layered precursors and a zeolite discovered via combinatorial chemistry techniques

, 2007
Abstract A combinatorial chemistry investigation screening the abilities of the diethyldimethylammonium (DEDMA), ethyltrimethylammonium (ETMA), and [Me 3 N(CH 2 ) 4 NMe 3 ] 2+ (diquat-4, DQ-4) cations to form zeolites over a range of conditions was carried out.
Mark A. Miller, Michael G. Gatter, Richard R. Willis, Robert W. Broach, Lisa M. Knight, Susan C. Koster, Annabelle I. Benin, Gregory J. Lewis   +7 more
openaire   +3 more sources

Analytical Techniques in Combinatorial Chemistry [PDF]

, 2000
openaire   +2 more sources

Analytical Techniques in Combinatorial Chemistry Edited by Michael Swartz. Marcel Dekker, New York. 2000. xii + 301 pp. 15.5 × 23.5 cm. ISBN 0-8247-1939-5. $150.00.

Journal of Medicinal Chemistry, 2000
Robert G. Gentles
openaire   +3 more sources

HighlightAnalytical Techniques for Single Bead Analysis in Combinatorial Chemistry

Analytical Communications, 1997
Mark Bradley, Vinay Swali
openaire   +3 more sources

Analytical Techniques in Combinatorial Chemistry: MAS CH Correlation in Solvent-Swollen Resin

The Journal of Organic Chemistry, 1995
Mary Ann Jarema, Robert C. Anderson, Martine Ziliox, Michael J. Shapiro, John P. Stokes   +4 more
openaire   +3 more sources