Results 151 to 160 of about 51,303 (237)

Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay. [PDF]

Drug Deliv Transl Res, 2022
Tutty MA, Vella G, Vennemann A, Wiemann M, Prina-Mello A.   +4 more
europepmc   +1 more source

RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA

Cell Proliferation, EarlyView.
Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3‐induced oxidative stress in HCC. Our study represents a valuable treatment strategy combining indisulam and an oxidative stress inducer in HCC. ABSTRACT Targeting base excision repair (BER) has been an attractive strategy in cancer therapeutics.
Hongda An, Anliang Xia, Siyuan Liu, Dongjun Luo, Longpo Geng, Binghua Li, Beicheng Sun, Zhu Xu   +7 more
wiley   +1 more source

The application of comet assay in monitoring of the immunosuppression level in a patient with toxic epidermal necrolysis: A case report

Burns Open, 2017
Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový, M. Matejovičová, H. Řihová, D. Štikarovská, L. Novotná, M. Hlaváčová, H. Paulová, I. Suchánek, P. Brychta   +8 more
doaj  

Antioxidant and genoprotective effects of osthole against cadmium-induced DNA damage: an in vitro study using comet assay. [PDF]

Res Pharm Sci, 2022
Vahidifar E, Sajjadi SE, Etebari M.
europepmc   +1 more source

Defining terminology and outcome measures for evaluating overdose response technology: An international Delphi study

Drug and Alcohol Review, EarlyView.
Abstract Introduction Various novel harm reduction services leverage technology to reduce the rising number of drug poisoning deaths, particularly among those who use drugs alone. There is significant variability in terminology and outcome measures in reporting these interventions, complicating efforts to build a comprehensive knowledge base.
William Rioux, Dylan Viste, Navid Sedaghat, Nathan Rider, Joseph Tay Wee Tek, Melissa Perri, David G. Schwartz, Kim Ritchie, Giuseppe Carrà, Stephanie Carreiro, Oona Kreig, Gabriela Marcu, Joseph Arthur, Joanne Cogdell, Mike Brown, Tyler Marshall, S. Monty Ghosh   +16 more
wiley   +1 more source

Correction: Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay. [PDF]

Drug Deliv Transl Res, 2022
Tutty MA, Vella G, Vennemann A, Wiemann M, Prina-Mello A.   +4 more
europepmc   +1 more source

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

The FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti, Silvio Aprile, David Cabañero, Fabio Travagin, Laura Butron, Gregorio Fernández‐Ballester, Gian Cesare Tron, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel, Ubaldina Galli   +9 more
wiley   +1 more source

Protective effects of Paeonia suffruticosa callus extract in skin through anti‐inflammation and repair UVB‐induced damage

International Journal of Cosmetic Science, EarlyView.
Peony callus extract (PCE) is beneficial for skin anti‐ageing and sensitivity induced by UVB radiation, through decreasing the level of inflammatory factors and matrix metalloproteinases. Furthermore, our research indicates that PCE effectively improves the total collagen content in human skin. Abstract Objective The study investigated effects of peony
Yufan Li, Jiejun Han, Rongyue Gong, Yuankun Liu, Yu Zhou, Tiangui Gong, Bin Wang, Laidi Zhang, Shuodan Li, Jiayue Chen   +9 more
wiley   +1 more source

Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis. [PDF]

Aging Cell, 2022
Copp ME, Chubinskaya S, Bracey DN, Shine J, Sessions G, Loeser RF, Diekman BO.   +6 more
europepmc   +1 more source

From pulp to cementum: 3D visualization of soft and hard dental tissues using different ex vivo nano‐CT contrast‐enhancement techniques

International Endodontic Journal, EarlyView.
Abstract Aim To determine the effect of two contrast‐enhancement strategies in nano‐computed tomography (nano‐CT) imaging on the contrast‐to‐noise ratio (CNR) of various dental tissues, including pulp, dentine and cementum, with the goal of enhancing the visibility of dental soft tissues to a level not yet reported in laboratory nano‐CT imaging ...
Torben Hildebrand, Håvard Jostein Haugen, Mario Romandini, Gianluca Plotino, Liebert Parreiras Nogueira   +4 more
wiley   +1 more source