Results 191 to 200 of about 1,931,388 (325)

The comet assay in animal models: From bugs to whales - (Part 1 Invertebrates).

open access: yesMutation research, 2019
G. Gajski   +12 more
semanticscholar   +1 more source

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

open access: yesCell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee   +13 more
wiley   +1 more source

CometAnalyser: A user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis. [PDF]

open access: yesComput Struct Biotechnol J, 2022
Beleon A   +8 more
europepmc   +1 more source

The comet assay in animal models: From bugs to whales - (Part 2 Vertebrates).

open access: yesMutation research, 2019
G. Gajski   +12 more
semanticscholar   +1 more source

RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA

open access: yesCell Proliferation, EarlyView.
Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3‐induced oxidative stress in HCC. Our study represents a valuable treatment strategy combining indisulam and an oxidative stress inducer in HCC. ABSTRACT Targeting base excision repair (BER) has been an attractive strategy in cancer therapeutics.
Hongda An   +7 more
wiley   +1 more source

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