Results 261 to 270 of about 57,805 (348)

Comet assay application for determining genotoxicity of veterinary vaccines preparations

, 2010
S. М. Dybkova, M. Romanko, Т. Г. Грузина, Л. С. Рєзніченко, Z. R. Ulberg, Валерій Олександрович Ушкалов, А. М. Головко   +6 more
openalex   +1 more source

Toxic Evaluations of Calea phyllolepis Extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate and Its In Silico Prediction of the Toxicity

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
In vivo and in silico toxicological effects of Calea phyllolepis extracts Standardized on 6‐epi‐β‐Verbesinol Coumarate. ABSTRACT Medicinal plants are traditionally used in folk medicine. Still, there is a misconception about the safety/efficacy of natural treatments, which results in few studies on the toxic, genotoxic, and mutagenic potential of ...
Suele Bierhals Vencato, Guilherme Borsoi, Cleverson Feistel, Mariele Feiffer Charão, Angélica Rocha Joaquim, Jaqueline Nascimento Picada, Alexandre de Barros Falcão Ferraz   +6 more
wiley   +1 more source

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling. [PDF]

Nucleic Acids Res
Bivehed E, Hellman B, Wenson L, Stenerlöw B, Söderberg O, Heldin J.   +5 more
europepmc   +1 more source

Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. [PDF]

Nat Protoc, 2020
Møller P, Azqueta A, Boutet-Robinet E, Koppen G, Bonassi S, Milić M, Gajski G, Costa S, Teixeira JP, Costa Pereira C, Dusinska M, Godschalk R, Brunborg G, Gutzkow KB, Giovannelli L, Cooke MS, Richling E, Laffon B, Valdiglesias V, Basaran N, Del Bo' C, Zegura B, Novak M, Stopper H, Vodicka P, Vodenkova S, de Andrade VM, Sramkova M, Gabelova A, Collins A, Langie SAS.   +30 more
europepmc   +1 more source

Automating Synthetic Organic Electrochemistry: Concepts and Advancements

Chemistry–Methods, Volume 5, Issue 12, November 2025.
A tutorial review on how to build an automated electrochemical flow platform, including the most relevant progresses and the future directions of the field, is studied. Automated electrochemical platforms are attracting attention for their potential in streamlining reaction preparation, electrolysis, and analysis to generate large datasets in a fast ...
Eduardo Rial‐Rodríguez, C. Oliver Kappe, Gabriele Laudadio   +2 more
wiley   +1 more source

A Preliminary Study on DNA Damage in Peripheral Blood of Cancer Patients After Radiotherapy with Comet Assay

, 2020
Darlina Yusuf, Tur Rahardjo, Viria Agesti Suvivan   +2 more
openalex   +1 more source

Assessing Second‐Line Treatment Strategies and Outcomes in Epidermal Growth Factor Receptor (EGFR) Oncogene‐Driven Stage IV Non‐Small Cell Lung Cancer, Following a First‐Line EGFR‐TKI Therapy

Cancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Oncogene‐driven metastatic non‐small cell lung cancer (mNSCLC) is associated with poor survival outcomes, despite advancements in first‐line tyrosine kinase inhibitor (TKI) therapies. Aims This study aimed to characterise second‐line treatment strategies for epidermal growth factor receptor (EGFR)‐driven mNSCLC, and to evaluate ...
Meghana Maddula, Annelise Decaria, Bea Brown, John Simes, Michael Boyer, Venessa Chin   +5 more
wiley   +1 more source

Metabolic enzyme PFKFB3 mediates matrix stiffness‐potentiated tumour growth and radiotherapeutic resistance in HCC

Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.
This study proposes a stiffness‐triggered pathway that co‐opts PFKFB3 expression and localization to fuel HCC growth and compromise radiotherapy efficacy. Specifically, matrix stiffness suppresses PFKFB3 ubiquitination by downregulating E3 ubiquitin ligase NEDD4 expression, and then enhances the stablity of PFKFB3 protein to increase glycolysis ...
Mimi Wang, Jiajun Li, Jiali Qian, Xi Zhang, Miao Li, Yingying Zhao, Zhiming Wang, Kun Guo, Dongmei Gao, Yan Zhao, Rongxin Chen, Zhenggang Ren, Taiwei Sun, Fan Wang, Jiefeng Cui   +14 more
wiley   +1 more source

Relevance of Comet Assay and Phosphorylated-Hsp90α in Cancer Patients' Peripheral Blood Leukocytes as Tools to Assess Cisplatin-based Chemotherapy Clinical Response and Disease Outcome. [PDF]

J Histochem Cytochem
Sottile ML, Gómez LC, Redondo A, Ibarra J, García MB, Gonzalez L, Vargas-Roig LM, Nadin SB.   +7 more
europepmc   +1 more source

B-Comet Assay (Comet Assay on Buccal Cells) for the Evaluation of Primary DNA Damage in Human Biomonitoring Studies. [PDF]

Int J Environ Res Public Health, 2020
Russo C, Acito M, Fatigoni C, Villarini M, Moretti M.   +4 more
europepmc   +1 more source