Results 21 to 30 of about 889,387 (243)
Comet assay on mice testicular cells
Frontiers in Genetics, 2015 Heritable mutations may result in a variety of adverse outcomes including genetic disease in the offspring. In recent years the focus on germ cell mutagenicity has increased and the “Globally Harmonized System of Classification and Labelling of ...
Anoop Kumar Sharma
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OpenComet: An automated tool for comet assay image analysis
Redox Biology, 2014 Reactive species such as free radicals are constantly generated in vivo and DNA is the most important target of oxidative stress. Oxidative DNA damage is used as a predictive biomarker to monitor the risk of development of many diseases.
Benjamin M. Gyori +4 more
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Biochemical Society Transactions, 2009 The single-cell gel electrophoresis technique or comet assay is widely regarded as a quick and reliable method of analysing DNA damage in individual cells. It has a proven track record from the fields of biomonitoring to nutritional studies.
McArt, Darragh
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The Comet Assay in Marine Animals
, 2019 Comet assay is a quick and versatile technique for assessing DNA damage in individual cells. It allows for the detection of DNA single- and double-strand breaks, as well as the presence of alkali labile sites and cross-links.
Giada Frenzilli +5 more
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Journal of Medical Physics, 2023 Purpose: This study aims to investigate the use of the neutral comet assay to assess deoxyribonucleic acid (DNA) damage in lymphocytes exposed to high doses of radiation.
Jose Solomon Raj +7 more
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Diagnostics, 2022 Comet assay is a simple and precise method to analyze DNA damage. Nowadays, many research studies have demonstrated the effectiveness of buccal mucosa cells usage in comet assays.
Afiahayati +3 more
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Neutral Comet Assay to Detect and Quantitate DNA Double-Strand Breaks in Hematopoietic Stem Cells
Bio-Protocol, 2021 In vertebrates, hematopoietic stem cells (HSCs) regulate the supply of blood cells throughout the lifetime and help to maintain homeostasis. Due to their long lifespan, genetic integrity is paramount for these cells, and accordingly, a number of stem ...
Irene Roy, Pon Nadar, Satish Khurana
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Abstracts of the 12th International Comet Assay Workshop held at the University of Navarra, Pamplona, Spain, 29–31 August 2017 (https://icaw.vito.be/) [PDF]
, 2017 Genotoxicity evaluation is a valuable tool for studying the most important occupational hazards allowing a reasonable epidemiological evaluation of potential health effects.
Morais, Simone +22 more
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New Application of the Comet Assay [PDF]
Journal of Histochemistry & Cytochemistry, 2011 The comet assay is a well-established, simple, versatile, visual, rapid, and sensitive tool used extensively to assess DNA damage and DNA repair quantitatively and qualitatively in single cells. The comet assay is most frequently used to analyze white blood cells or lymphocytes in human biomonitoring studies, although other cell types have been ...
Elva I, Cortés-Gutiérrez +5 more
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Comet Assay measurements: a perspective [PDF]
Cell Biology and Toxicology, 2007 The Comet Assay or single cell gel electrophoresis assay is one of the very widely used assays to microscopically detect DNA damage at the level of a single cell. The determination of damage is carried out either through visual scoring of cells (after classification into different categories on the basis of tail length and shape) or by using different ...
Kumaravel, T. S. +3 more
openaire +2 more sources