Results 291 to 300 of about 57,805 (348)
Informing Decision‐Making About Caesarean Birth: A Delphi Study to Develop a Core Information Set
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 13, Page 2024-2039, December 2025.ABSTRACT Objective To develop a caesarean birth core information set. Caesareans are the most common surgery performed in many countries. Women need information for informed decision‐making and consent. Core information sets (CISs) provide baseline information, agreed upon by parents and clinicians, for discussion before a procedure.
Carol Kingdon +50 more
wiley +1 more source
Journal of Diabetes, Volume 17, Issue 12, December 2025.SGLT2i reduced the frequency of intravitreal ranibizumab injections in a subgroup of patients with both diabetic macular edema and hypertension, demonstrating a potential synergistic effect. ABSTRACT Aims To evaluate the feasibility of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) as a systemic adjunct for patients with diabetic macular edema (DME)
Ryoichi Ishibashi +6 more
wiley +1 more source
Antimicrobial prescribing guidelines for horses in Australia
Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt +18 more
wiley +1 more source
Cancer Science, Volume 116, Issue 12, Page 3403-3416, December 2025.This study identified LIG1 as a novel synthetic lethality‐inducing factor in prostate cancer through a genome‐wide CRISPR‐Cas9 knockout screen and demonstrated that its inhibition enhances the efficacy of PARP inhibitor. The combination of L82‐G17 and olaparib showed synergistic antitumor effects both in vitro and in vivo, offering a promising ...
Masaru Tani +22 more
wiley +1 more source
Colorectal Disease, Volume 27, Issue 12, December 2025.Abstract Background Anastomotic leak (AL) following rectal cancer resection significantly increases the clinical care, risks morbidity and mortality and impairs oncological outcomes. AL management is not standardised. This systematic review and pooled analysis evaluated the comparative efficacy of the various reported strategies.
Ruth Walsh +3 more
wiley +1 more source
Clinical and Translational Science, Volume 18, Issue 12, December 2025.ABSTRACT The onset of the global COVID‐19 pandemic created an urgent need for therapeutic monoclonal antibody (mAb) development, while the rapid mutation of the SARS‐CoV‐2 virus and emergence of new variants presented a moving target for validation of efficacy. Since it is virtually impossible to conduct randomized controlled trials in the context of a
Qianwen Wang +7 more
wiley +1 more source
ASSESSMENT OF ALUMINUM INDUCED GENOTOXICITY WITH COMET ASSAY IN WHEAT, RYE AND TRITICALE ROOTS
, 2015 Filiz Vardar +3 more
openalex +1 more source
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Biochemical Society Transactions, 2009
The single-cell gel electrophoresis technique or comet assay is widely regarded as a quick and reliable method of analysing DNA damage in individual cells. It has a proven track record from the fields of biomonitoring to nutritional studies. The assay operates by subjecting cells that are fixed in agarose to high salt and detergent lysis, thus removing
Darragh G, McArt +4 more
openaire +2 more sources
The single-cell gel electrophoresis technique or comet assay is widely regarded as a quick and reliable method of analysing DNA damage in individual cells. It has a proven track record from the fields of biomonitoring to nutritional studies. The assay operates by subjecting cells that are fixed in agarose to high salt and detergent lysis, thus removing
Darragh G, McArt +4 more
openaire +2 more sources