Results 61 to 70 of about 1,956,113 (201)
A Study of Cytogenetic Stability of Induced Pluripotent Stem Cells Using Karyotyping and Comet Assay Techniques [PDF]
Journal of Kerman University of Medical Sciences, 2015 Background & Aims: Induced pluripotent stem cells (iPSCs) have the capability to undergo unlimited selfrenewal and differentiation into all cell types in the body.
Payam Ghasemi-Dehkordi +7 more
doaj
Sperm DNA damage output parameters measured by the alkaline Comet assay and their importance
Andrologia, 2017 The alkaline Comet assay has shown high diagnostic value to determine male reproductive health and prognostic ability to predict ART success. Here, spermatozoon was analysed in 47 fertile donors and 238 patients, including 132 couples undergoing ART ...
L. Simon +4 more
semanticscholar +1 more source
Genomic instability in patients with type 2 diabetes mellitus on hemodialysis
Revista Brasileira de Hematologia e Hemoterapia, 2012 OBJECTIVE: A previous study by our research group evaluated the levels of DNA damage using the comet assay in hemodialysis patients with type 2 diabetes mellitus. The same blood samples were also evaluated using the cytochalasin B micronucleus assay.
Roberta Passos Palazzo +4 more
doaj +1 more source
DNA damage in buccal cells in oral PMDs and malignant disorders by comet assay
Brazilian Journal of Oral Sciences, 2019 Aim: DNA damage associated with Oral Squamous Cell Carcinoma (OSCC) and potentially malignant disorders (PMDs) is produced due to carcinogenic agents or increased oxidative stress. Comet assay can assist in early detection and evaluation of the amount of
Garima Rawat +3 more
doaj +1 more source
Detection of Hypoxia in Human Brain Tumor Xenografts Using a Modified Comet Assay
Neoplasia: An International Journal for Oncology Research, 2003 We used the standard comet assay successfully to generate in vitro dose-response curves under oxic and hypoxic conditions. We then made mixtures of cells that had been irradiated with 3 and 9 Gy of X-rays to simulate two subpopulations in a tumor, but ...
Jingli Wang +8 more
doaj +1 more source
Overestimation of nanoparticles-induced DNA damage determined by the comet assay
Nanotoxicology, 2016 The increasing use of engineered nanoparticles (NPs) in a wide range of commercial products raises concern about the possible risks that NPs pose to human health.
Daniela Ferraro +4 more
semanticscholar +1 more source
Brazilian Journal of OceanographyAquaculture production is continuously growing worldwide, and marine fish farming in Brazil is still in its infancy. Intensive farming conditions may cause physiological stress to the cultured organism, which can be evaluated by citogenotoxic biomarkers.
Marina Tenório Botelho +7 more
doaj +1 more source
Burns Open, 2017 Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový +8 more
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The comet assay – how to recognise “good data”
Frontiers in Genetics, 2015 Testing of potentially genotoxic materials currently involves use of in vitro assays such as the Ames test (gene mutations), the chromosome aberration assay and in vitro micronucleus assay (predominantly using human peripheral lymphocytes to detect ...
William Barfield
doaj +1 more source