Results 41 to 50 of about 8,069 (192)
Salud Pública de México, 2001 Objective. To assess the genotoxic activity of N-nitroso diethylamine (NDEA), maleic hydrazide (MH), and ethyl methane sulfonate (EMS) using two systems: the comet assay on nuclei from Tradescantia, and the pink mutation test on Tradescantia staminal ...
Alvarez-Moya Carlos +5 more
doaj
Modified comet assays for the detection of cyclobutane pyrimidine dimers and oxidative base damages
Journal of Radiation and Cancer Research, 2017 The comet assay (also known as single-cell gel electrophoresis) is a technique for the detection of DNA damage at the level of the individual cell. It is a versatile, relatively simple to perform and sensitive method.
Ganesan Muthusamy +6 more
doaj +1 more source
FUV Observations of the Inner Coma of 46P/Wirtanen
The Planetary Science Journal, 2021 Far-ultraviolet observations of comets yield information about the energetic processes that dissociate the sublimated gases from their primitive surfaces.
John W. Noonan +8 more
doaj +1 more source
Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity
Advanced Science, EarlyView.We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng +11 more
wiley +1 more source
Comet Nuclei Composition and Evolution
Thanks to Rosetta orbiter's and Philae lander's data our knowledge of cometary nuclei composition has experienced a great advancement. The properties of 67P/CG nucleus are discussed and compared with other comets explored in the past by space missions.
Filacchione, Gianrico +3 more
openaire +2 more sources
Hubble Space Telescope Observations of the Interstellar Interloper 3I/ATLAS
The Astrophysical Journal LettersWe present high-angular-resolution observations of the third known interstellar interloper, 3I/ATLAS, from the Hubble Space Telescope. The object is clearly active at 3.8 au preperihelion, showing dust emitted from the hot, Sun-facing side of the nucleus
David Jewitt +4 more
doaj +1 more source
Physics Letters B, 2017 The experimental sensitivity to μ→e conversion on nuclei is expected to improve by four orders of magnitude in coming years. We consider the impact of μ→e flavour-changing tensor and axial-vector four-fermion operators which couple to the spin of ...
Vincenzo Cirigliano +2 more
doaj +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, EarlyView.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays
Genetics and Molecular Biology, 2011 Glyphosate is noted for being non-toxic in fishes, birds and mammals (including humans). Nevertheless, the degree of genotoxicity is seriously controversial.
Carlos Alvarez-Moya +5 more
doaj
DNA damage induced by mutagens in plant and human cell nuclei in acellular comet assay.
Folia Histochemica et Cytobiologica, 2006 Higher plant cells have a long tradition of use in the studies on environmental mutagenesis in situ, especially in relation to human health risk determination.
Jolanta Maluszynska +2 more
doaj +1 more source