Results 31 to 40 of about 144,914 (237)

Exocomets size distribution in the $$\beta$$ β Pictoris planetary system

Scientific Reports, 2022
The star $$\beta$$ β  Pictoris harbors a young planetary system of about 20 million years old, which is characterized by the presence of a gaseous and dusty debris disk, at least two massive planets and many minor bodies.
Alain Lecavelier des Etangs, Lucie Cros, Guillaume Hébrard, Eder Martioli, Marc Duquesnoy, Matthew A. Kenworthy, Flavien Kiefer, Sylvestre Lacour, Anne-Marie Lagrange, Nadège Meunier, Alfred Vidal-Madjar   +10 more
doaj   +1 more source

Cytotoxicity and Genotoxicity Evaluation of Fluorapatite/bioactive Glass Nanocomposite Foams With Two Various Weight Ratios as Bone Tissue Scaffold: an in vitro study [PDF]

Iranian Journal of Materials Science and Engineering, 2022
The optimization of biomaterials biodegradation rate similar to tissue regeneration, is one of the main goals in the field of tissue engineering. However, the necessity to assess their possible toxicity is always considered.
Ebrahim Zabihi, Roghayeh Pourbagher, Seyedali Seyedmajidi   +2 more
doaj  

Assessment of Cellular Damage by Comet Assay After Photodynamic Therapy in vitro

Acta Medica, 2004
The aim of this study was analysis of DNA damage in the cell line of the human melanoma G361 after photodynamic therapy (PDT) by comet assay. Photodynamic therapy is based on cytotoxic action of sensitizers (10 µM ZnTPPS4 fixed into 1 mM cyclodextrin ...
Jaroslav Maceček, Hana Kolářová, Jitka Psotová, Robert Bajgar, Martin Huf, Pavla Nevřelová, Marek Tomečka, Jiří Mosinger   +7 more
doaj   +1 more source

Identification of Shigella flexneri IcsA residues affecting interaction with N-WASP, and evidence for IcsA-IcsA co-operative interaction. [PDF]

PLoS ONE, 2013
The Shigella flexneri IcsA (VirG) protein is a polarly distributed outer membrane protein that is a fundamental virulence factor which interacts with neural Wiskott-Aldrich syndrome protein (N-WASP). The activated N-WASP then activates the Arp2/3 complex
Min Yan Teh, Renato Morona
doaj   +1 more source

Actin comet tails, endosomes and endosymbionts [PDF]

Journal of Experimental Biology, 2003
SUMMARYThe Arp2/3 complex consists of seven highly conserved and tightly associated subunits, two of which are the actin-related proteins Arp2 and Arp3. One of the best-studied functions of the Arp2/3 complex is to stimulate actin nucleation and force production at the leading edge of motile cells.
Kammy, Fehrenbacher, Thomas, Huckaba, Hyeong-Cheol, Yang, Istvan, Boldogh, Liza, Pon   +4 more
openaire   +2 more sources

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

Advanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu, Chenchen Zhu, Xuelin Yao, Yi Liu, Jing Zhu, Yuebo Li, Hanjie Xu, Cheng Peng, Ge Shan, Liang Chen, Ying Zhou   +10 more
wiley   +1 more source

Characterization of the Dust and Sodium Tails of Comet C/2020 F3 (NEOWISE) from Parker Solar Probe and Amateur Observations

The Planetary Science Journal
Comet C/2020 F3 (NEOWISE) reached perihelion on 2020 July 3 at 0.29 au and exhibited a highly structured dust tail. Using a simplified Finson–Probstein model, structures such as striae, observed in the tail in images obtained by the Parker Solar Probe ...
Qasim Afghan, Geraint H. Jones, Karl Battams, Oliver Price, Andrew J. Coates   +4 more
doaj   +1 more source

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source

Recurrent Cometary Activity Discovered on Quasi-Hilda Jupiter Family Comet 362P/(457175) 2008 GO98

The Astrophysical Journal Letters
We report the discovery of recurrent activity on quasi-Hilda comet (QHC) 362P/(457175) 2008 GO _98 . The first activity epoch was discovered during the perihelion passage of 362P in 2016, so we were motivated to observe it for recurrent cometary activity
Kennedy A. Farrell, Colin Orion Chandler, Chadwick A. Trujillo, William J. Oldroyd, Jarod A. DeSpain, Mark Jesus Mendoza Magbanua, Maxwell K. Frissell, Phineas Stone   +7 more
doaj   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source