Results 131 to 140 of about 2,938,052 (285)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Understanding Entrepreneurial Commitment: A Test of Side-Bet Theory
M@n@gementThis paper contributes to the burgeoning literature on entrepreneurial commitment by providing a first empirical investigation of Howard Becker’s side-bet theory in the context of nascent entrepreneurship. We investigate how different forms of commitment
Laëtitia Gabay-Mariani +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Human Resource Practices and Job Performance: Insights from Public Administration
SocietiesThe Moroccan government has taken several initiatives to improve HR practices in the public sector, with the aim of enhancing the performance of civil servants and thereby improving the quality of public administration services.
Zakaria Ouabi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Ação Ergonômica, 2003 This paper presents the results of a case study carried out in a large-scale Brazilian company, of the services sector, and the objective was to comprehend the questions of absenteeism and commitment at work.
Maria Irene Stocco Betiol +1 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
La sociologie au Maroc : retour réflexif et engagé d’un praticien
Sociologies, 2015 This paper tries to supply marks as regards the state of the Moroccan sociology in a reflexive and committed approach. Three main plans are investigated: 1) the question of the commitment, in its epistemological and historic dimensions; 2) the ...
Abdelmalek Ouard
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Sociologies, 2006 The term "commitment" is experiencing a growing success in sociological debates. In this article, the author examines the uses of the concept of commitment in order to understand the reasons for its growing popularity.
Howard S. Becker
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