Results 21 to 30 of about 109,095 (245)

Immunologic alterations in common variable immunodeficiency

Revista Alergia México, 2017
Common variable immunodeficiency (IDCV) is the largest group of symptomatic primary immune deficiencies; it is characterized by hypogammaglobulinemia, poor response to vaccines and increased susceptibility to infections.
Laura Berrón-Ruiz
doaj   +1 more source

Posner-Schlossman Syndrome in Common Variable Immunodeficiency

Case Reports in Ophthalmological Medicine, 2020
Introduction. Posner-Schlossman syndrome (PSS) is a rare glaucomatocyclitic crisis with clinical features including recurrent episodes of unilateral elevated intraocular pressure.
Madiha Huq, Neha Sanan, Phuong Daniels, Robert Hostoffer   +3 more
doaj   +1 more source

Assessment of the first presentations of common variable immunodeficiency in a large cohort of patients

BMC Immunology, 2023
Background Common Variable Immunodeficiency (CVID) is a primary immunodeficiency syndrome resulting in recurrent infections, autoimmunity, and granulomatous manifestations.
Hossein Esmaeilzadeh, Armita Jokar-Derisi, Amir Hossein Hassani, Reza Yazdani, Samaneh Delavari, Hassan Abolhassani, Negar Mortazavi, Aida Askarisarvestani   +7 more
doaj   +1 more source

Severe diabetic ketoacidosis and autoimmune pancreatitis with SIRS in an adolescent with LRBA deficiency – A rare complication of a common primary immunodeficiency disease

Journal of Family Medicine and Primary Care, 2022
Common variable immunodeficiency is the most common primary immunodeficiency disorder. Lipopolysaccharide (LPS)-responsive beige-like anchor protein (LRBA) deficiency is categorized as a common variable immunodeficiency associated with autoimmune ...
Divya Ravindran, Rajavel Sagul Ramanuja Mugunthan, Tarikere Krishnamurthy Shruthi, Dhaarani Jayaraman   +3 more
doaj   +1 more source

Common Variable Immunodeficiency and Circulating TFH

Journal of Immunology Research, 2016
CD4+ T follicular helper cells (TFH) were assessed in adult patients with common variable immune deficiency (CVID) classified according to the presence of granulomatous disease (GD), autoimmunity (AI), or both GD and AI (Group I) or the absence of AI and
Ana Coraglia, Nora Galassi, Diego S. Fernández Romero, M. Cecilia Juri, Marta Felippo, Alejandro Malbrán, María M. E. de Bracco   +6 more
doaj   +1 more source

Renal Evaluation in Common Variable Immunodeficiency

Journal of Immunology Research, 2018
Introduction. Common variable immunodeficiency (CVID) comprises a heterogeneous group of disorders characterized by impaired antibody production. Kidney involvement in CVID is described in isolated and sporadic case reports.
Giovany Gomes Capistrano, Gdayllon Cavalcante Meneses, Fernanda Macedo de Oliveira Neves, Renata de Almeida Leitão, Alice Maria Costa Martins, Alexandre Braga Libório   +5 more
doaj   +1 more source

A “strange” case of COPD

Clinical Management Issues, 2015
Common variable immunodeficiency (CVID) is a rare syndrome, characterized by hypogammaglobulinemia and limited antibody responses due to either impaired B-lymphocyte development or B-cell responses to T-lymphocyte signals.
Laura Massarelli, Valerio Tomaselli, Carlo Bussolino, Valter Saracco   +3 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source