Results 51 to 60 of about 1,261,912 (332)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The competency-based approach to training

Medical Journal of Indonesia, 1996
This paper describes the competency-based training (CBT) approach that was presented at a pre-congress seminar entitled "Learning Without Walls" that was held on October 13-14 1995 in Bali Indonesia in conjunction with the XVth Asian and Oceanic Congress of Obstetrics and Gynecology. A small group of decision makers was given the opportunity to update
Rick Sullivan, Noel McIntosh
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Efektivitas Pendekatan Scientific dengan Pbl dan Problem Solving untuk Meningkatkan Kompetensi dalam Pembelajaran IPS [PDF]

, 2016
This study aimed to compare the effectiveness of scientific approach with problem based learning and problem solving in teaching social studies to improve: attitude competence, knowledge competene, and skill competence.The population of the research was ...
Mulyani, E. (Endang), Setyowati, R. (Rini)   +1 more
core  

The development of the digital teaching competence from a sociocultural approach [PDF]

, 2019
En la actualidad, la competencia digital docente trasciende de la formación individual del profesorado en materia TIC. El marco europeo DigCompEdu incide en que el profesorado tiene que capacitar al alumnado en la aplicación de las tecnologías digitales ...
Colás Bravo, María Pilar, Conde Jiménez, Jesús, Reyes de Cózar, Salvador   +2 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Foreign language communicative competence forming of students studying at food production department (by the example of text book “food technology”)

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016
The article considers a problem of foreign-language communicative competence forming. Authors believe that training of foreign-language communicative activities with use of course book Food Technology helps students to use and understand foreign-language
Anna A. Khokhlova, Amaliya L. Kuregyan
doaj  

Revising the Assessment of Creative Competence of Journalism Students

RUDN Journal of Studies in Literature and Journalism, 2022
This study proposes an effective development methodology for evaluating the creativity of journalism students. Within the framework of university education, it is proposed to focus the attention of teachers on creating a special educational environment ...
Viktor V. Gavrilov
doaj   +1 more source

COMPETENCE-BASED APPROACH TO LSP-TRANSLATION

Philology at MGIMO, 2020
The article presents the model of professional translator competences related to three levels of the ‘second language personality’. The article describes the development of translator competences (communicative, extra-linguistic and specialized ones) on the basis of the well-formed competence in the basic branch of study (the student’s major).
M. Ye. Korovkina, A. L. Semenov, V. I. Ershov   +2 more
openaire   +2 more sources

Weighting Scheme for a Pairwise Multi-label Classifier Based on the Fuzzy Confusion Matrix

, 2018
In this work we addressed the issue of applying a stochastic classifier and a local, fuzzy confusion matrix under the framework of multi-label classification. We proposed a novel solution to the problem of correcting label pairwise ensembles.
Kurzynski, Marek, Trajdos, Pawel
core   +1 more source