Results 151 to 160 of about 1,304,895 (387)

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

open access: yesAdvanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang   +13 more
wiley   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

Pengaruh Kompetensi Sumberdaya Manusia dan Manajerial terhadap Kualitas Laporan Keuangan (Survey pada Dppkad Kabupaten Buol) [PDF]

open access: yes, 2017
Act Number 17 of 20033, Act No. 1 of 20044 and Government Rule Number 24 of 2005 which has been changed with PP number 71 of 2010 about the Government Accounting Standard.
Zahrah, S. (Siti)
core   +1 more source

Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene

open access: yesAdvanced Science, EarlyView.
A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain   +5 more
wiley   +1 more source

PENGARUH KOMPETENSI SUMBER DAYA MANUSIA DAN PENERAPAN PENGENDALIAN INTERN TERHADAP PENERAPAN AKUNTANSI BERBASIS AKRUAL DAN DAMPAKNYA TERHADAP KUALITAS INFORMASI PELAPORAN KEUANGAN (STUDI PADA SATKER DI KANTOR WILAYAH KEMENTERIAN AGAMA PROVINSI ACEH) [PDF]

open access: yes, 2016
THE EFFECT OF COMPETENCE OF HUMAN RESOURCES AND APPLICATION OF INTERNAL CONTROLON ACCRUAL BASED ACCOUNTING APPLICATION AND ITS IMPACT ON THE QUALITY OF FINANCIAL REPORTING INFORMATION(STUDY AT REGIONAL OFFICE WORK UNIT RELIGIOUS MINISTRY OF ACEH PROVINCE)
Fahriani
core  

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine From Xylose in Escherichia Coli

open access: yesAdvanced Science, EarlyView.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han   +5 more
wiley   +1 more source

How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?

open access: yesAdvanced Science, EarlyView.
This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen   +5 more
wiley   +1 more source

Foreign labor, peer‐networking and agricultural efficiency in the Italian dairy sector

open access: yesAgribusiness, EarlyView.
Abstract While the presence of immigrants in the agricultural sector is widely acknowledged, the empirical evidence on its economic consequences is lacking, especially from a microeconomic perspective. Using the Farm Accountancy Data Network panel data for Italian dairy farms in the period 2008–2018, the present study investigates the relationship ...
Federico Antonioli   +2 more
wiley   +1 more source

COMPETENCY BASED HUMAN RESOURCES DEVELOPMENT

open access: yesJurnal Administrasi Pendidikan
This study aims to increase the Civil Servant Professionality Index of Sungai Penuh City from the competency dimension. The methodology of this research is descriptive qualitative by using SWOT analysis method. Competency dimensions are measured from indicators of competency development history that have been carried out, for example: leadership ...
Sari, Ratih Despita   +2 more
openaire   +1 more source

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