Results 81 to 90 of about 530,705 (304)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

An integrated approach : holistic assessment of vocational trainees in the NZ dairy farming industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education (Tertiary Education) at Massey University, Manawatu, New Zealand [PDF]

, 2016
Vocational training qualifications in New Zealand have undergone significant change since 2008 due to the Targeted Review of Qualifications (TRoQ) initiated by the New Zealand Qualifications Authority (NZQA).
Couper, Graeme William
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Competence By Design: a transformational national model of time-variable competency-based postgraduate medical education

Perspectives on Medical Education
Postgraduate medical education is an essential societal enterprise that prepares highly skilled physicians for the health workforce. In recent years, PGME systems have been criticized worldwide for problems with variable graduate abilities, concerns ...
Jason R. Frank, Jolanta Karpinski, Jonathan Sherbino, Linda S. Snell, Adelle Atkinson, Anna Oswald, Andrew K. Hall, Lara Cooke, Susan Dojeiji, Denyse Richardson, Warren J. Cheung, Rodrigo B. Cavalcanti, Timothy R. Dalseg, Brent Thoma, Leslie Flynn, Wade Gofton, Nancy Dudek, Farhan Bhanji, Brian M.-F. Wong, Saleem Razack, Robert Anderson, Daniel Dubois, Andrée Boucher, Marcio M. Gomes, Sarah Taber, Lisa J. Gorman, Jane Fulford, Viren Naik, Kenneth A. Harris, Rhonda St. Croix, Elaine van Melle   +30 more
doaj   +1 more source

Review of Implementation Values of Character In The Subject On Vocational Education [PDF]

, 2017
The objective of this research is to develop the competency-based learning the electricity by integrating character education (Model-PKBK) in Vocational High School.
Arfandi, Anas, Mangesa, Riana Tangkin
core  

On being a mentor [PDF]

, 2013
This article explores issues relating to mentoring students, particularly ophthalmic nursing students. It highlights the importance of mentorship in learning in practice, which in turn is critical to students' education in a competency-based profession ...
Cox, C. L., Jones, M, Rutkowski, K
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Competency-Based Medical Education at Scale: A Road Map for Transforming National Systems of Postgraduate Medical Education

Perspectives on Medical Education
In the past decade, the Canadian system of postgraduate medical education has been transformed with the implementation of a new approach to competency based medical education called Competence by Design.
Jolanta Karpinski, Jennifer Stewart, Anna Oswald, Timothy R. Dalseg, Adelle Atkinson, Jason R. Frank   +5 more
doaj   +1 more source

Reimagining our views on medical education: Part 1

Archives of Medicine and Health Sciences, 2018
As medical educators, we are continually challenged to prepare the next generation of physicians. This means providing the skills and knowledge to those who will provide health care for years to come. Given the continually changing health-care landscape,
Elizabeth M Wooster, Jerry M Maniate
doaj   +1 more source

The objective structured public health examination (OSPHE): work-based learning for a new exam [PDF]

, 2007
Introduction: Postgraduate education for all healthcare professionals is shifting from traditional knowledge-based models towards competency-based training and assessment.
Ali, Ayesha
core