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Retraction: Prader-Willi region non-protein coding RNA 1 suppressed gastric cancer growth as a competing endogenous RNA of miR-425-5p. [PDF]
Clin Sci (Lond)europepmc +1 more source
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Competing endogenous RNA regulation in hematologic malignancies
Clinica Chimica Acta, 2020The clinical application of cytogenetic analysis and molecular-targeted drugs has dramatically improved the prognosis for many patients with hematologic malignancy, especially for those with chronic myeloid leukemia (CML) and acute promyelocytic leukemia (APL).
Simin Liang
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Competing Endogenous RNAs (ceRNAs) in Colorectal Cancer: A Review
Expert Reviews in Molecular Medicine, 2022Abstract Colorectal cancer (CRC) is a common type of cancer and the second leading cause of cancer-related deaths worldwide. Competing endogenous RNAs (ceRNAs) that contain microRNA response elements (MREs) are involved in CRC progression. They can compete with microRNAs (miRNAs) via their MREs, which can combine non-coding and coding RNAs via ...
Mohammad Hossein Akhbari +2 more
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A new algorithm for predicting competing endogenous rnas
Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), 2012Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regulation across the transcriptome and thus expand the function of microRNAs. CeRNAs have been shown to play important roles in disease like cancer [1].
Mario Flores, Yufei Huang 0001
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Posttranscriptional Regulation of PTEN by Competing Endogenous RNAs
2015PTEN expression can be dysregulated in cancers via multiple mechanisms including genomic loss, epigenetic silencing, transcriptional repression, and posttranscriptional regulation by microRNAs. MicroRNAs are short, noncoding RNAs that regulate gene expression by binding to recognition sites on target transcripts.
Yvonne, Tay, Pier Paolo, Pandolfi
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Competing Endogenous RNAs in Hepatocellular Carcinoma—The Pinnacle of Rivalry
Seminars in Liver Disease, 2019AbstractThe role of noncoding transcripts in gene expression is nowadays acknowledged to keep various diseases at bay—despite being referred to as “junk” DNA several years ago. Believed to be at the heart of multiple regulatory pathways, microRNAs (miRNAs) are small noncoding RNAs (ncRNAs) involved in posttranscriptional gene regulation.
Abdelrahman Yousry, Afify +5 more
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A Method for Constructing an Integrative Network of Competing Endogenous RNAs
2021Since the new gene regulation involving competing endogenous RNA (ceRNA) interactions targeted by common microRNAs (miRNAs) was found, several computational methods have been proposed to derive ceRNA networks. However, most of the ceRNA networks are restricted to represent either miRNA-target RNA interactions or lncRNA-miRNA-mRNA interactions. From the
Seokwoo Lee +3 more
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Mimicry, deception and competition: The life of competing endogenous RNAs
WIREs RNA, 2019Since their discovery, small regulatory RNAs (sRNAs) were thought to be regulated exclusively at the transcriptional level. However, accumulating data from recent reports indicate that posttranscriptional signals can also modulate the function and stability of sRNAs.
Marc P, Grüll, Eric, Massé
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Competing Endogenous RNAs (CeRNAs): Novel Network in Neurological Disorders
Current Medicinal Chemistry, 2021Neurological disorders (NDs) comprise a broad range of diseases affecting both central and peripheral nervous systems. These complex multifactorial diseases have a high rate of mortality all over the world, particularly in aged people. Today, new evidence drove our attention to the notable role of noncoding RNAs (ncRNAs) in the progression of NDs ...
Sadra Samavarchi Tehrani +7 more
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