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Long non-coding RNA H19 and cancer: A competing endogenous RNA
Bulletin du Cancer, 2019Long non-coding RNA (lncRNA) is a class of non-coding RNA with a length of more than 200 nucleotides, which has become a hotspot in the research of tumorigenesis and development in recent years. Accumulating studies have indicated that H19 is abnormally expressed in human malignant tumors, and regulates cell proliferation, migration, invasion, anti ...
Yafen, Ye, Ao, Shen, Anwen, Liu
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A new algorithm for predicting competing endogenous rnas
Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), 2012Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regulation across the transcriptome and thus expand the function of microRNAs. CeRNAs have been shown to play important roles in disease like cancer [1].
Mario Flores, Yufei Huang
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Journal of Periodontal Research, 2018
Background and ObjectivesLong noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high‐throughput RNA sequencing and microarray data ...
S. Li +10 more
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Background and ObjectivesLong noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high‐throughput RNA sequencing and microarray data ...
S. Li +10 more
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Competing Endogenous RNA and Interactome Bioinformatic Analyses on Human Telomerase
Rejuvenation Research, 2014We present a classic interactome bioinformatic analysis and a study on competing endogenous (ce) RNAs for hTERT . The hTERT gene codes for the catalytic subunit and limiting component of the human telomerase complex.
Walter, Arancio +4 more
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Competing Endogenous RNAs in Hepatocellular Carcinoma—The Pinnacle of Rivalry
Seminars in Liver Disease, 2019AbstractThe role of noncoding transcripts in gene expression is nowadays acknowledged to keep various diseases at bay—despite being referred to as “junk” DNA several years ago. Believed to be at the heart of multiple regulatory pathways, microRNAs (miRNAs) are small noncoding RNAs (ncRNAs) involved in posttranscriptional gene regulation.
Abdelrahman Yousry, Afify +5 more
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[Research progress of competing endogenous RNA].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhiThe competing endogenous RNA (ceRNA) hypothesis is a new pattern of gene posttranscriptional regulation. Encoding mRNA, long noncoding RNA (lncRNA), pseudogene transcript, circular RNA (circRNA), etc. can regulate gene expression by binding microRNA (miRNA).
Lin, Wang, Jie, Liu
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[New mode of competing endogenous RNA: circular RNA].
Zhonghua wei zhong bing ji jiu yi xue, 2018Circular RNA (circRNA) is widely found in various species' cells.They have several characteristics including structural stability,high expression and expression in a tissue-specific manner.Recent studies have demonstrated that circRNA is a member of competing endogenous RNA (ceRNA).CircRNA regulate the expression of related RNA molecules via binding ...
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Competing endogenous RNA network in pulmonary arterial hypertension
International Journal of Cardiology, 2014Kai, Ma, Qian, Zhao, Shoujun, Li
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