Results 281 to 290 of about 1,773,606 (321)

Decoding competing endogenous RNA networks for cancer biomarker discovery

open access: yesBriefings in Bioinformatics, 2020
Crosstalk between competing endogenous RNAs (ceRNAs) is mediated by shared microRNAs (miRNAs) and plays important roles both in normal physiology and tumorigenesis; thus, it is attractive for systems-level decoding of gene regulation.
Xin Qi   +3 more
semanticscholar   +3 more sources

Long noncoding RNA lncRNA354 functions as a competing endogenous RNA of miR160b to regulate ARF genes in response to salt stress in upland cotton.

Plant, Cell and Environment, 2021
Long non-coding RNAs (lncRNAs) play important roles in response to biotic and abiotic stress through acting as competing endogenous RNAs (ceRNAs) to decoy mature miRNAs.
Xiaopei Zhang   +6 more
semanticscholar   +1 more source

Competing Endogenous RNAs (ceRNAs) in Colorectal Cancer: A Review

Expert Reviews in Molecular Medicine, 2022
Abstract Colorectal cancer (CRC) is a common type of cancer and the second leading cause of cancer-related deaths worldwide. Competing endogenous RNAs (ceRNAs) that contain microRNA response elements (MREs) are involved in CRC progression. They can compete with microRNAs (miRNAs) via their MREs, which can combine non-coding and coding RNAs via ...
Mohammad Hossein Akhbari   +2 more
openaire   +2 more sources

Competing endogenous RNA regulation in hematologic malignancies

Clinica Chimica Acta, 2020
The clinical application of cytogenetic analysis and molecular-targeted drugs has dramatically improved the prognosis for many patients with hematologic malignancy, especially for those with chronic myeloid leukemia (CML) and acute promyelocytic leukemia (APL).
Han, Xiao, Simin, Liang, Li, Wang
openaire   +2 more sources

Competing endogenous RNA (ceRNA) cross talk and language in ceRNA regulatory networks: A new look at hallmarks of breast cancer

Journal of Cellular Physiology, 2018
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide. Despite the substantial advancement in understanding the molecular mechanisms and management of BC, it remains the leading cause of cancer death in women.
Rasoul Abdollahzadeh   +5 more
semanticscholar   +1 more source

A new algorithm for predicting competing endogenous rnas

Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), 2012
Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regulation across the transcriptome and thus expand the function of microRNAs. CeRNAs have been shown to play important roles in disease like cancer [1].
Mario Flores, Yufei Huang 0001
openaire   +1 more source

A Method for Constructing an Integrative Network of Competing Endogenous RNAs

2021
Since the new gene regulation involving competing endogenous RNA (ceRNA) interactions targeted by common microRNAs (miRNAs) was found, several computational methods have been proposed to derive ceRNA networks. However, most of the ceRNA networks are restricted to represent either miRNA-target RNA interactions or lncRNA-miRNA-mRNA interactions. From the
Seokwoo Lee   +3 more
openaire   +1 more source

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