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Comprehensive Analysis of a Long Noncoding RNA-Associated Competing Endogenous RNA Network in Wilms Tumor [PDF]
Cancer Control, 2020 Long noncoding RNA (lncRNA) plays crucial roles in various biological processes of different cancers, especially acting as a competing endogenous RNA (ceRNA).
Libin Deng, Robert Mukiibi, Xu Zihao
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Competing endogenous RNAs: a target-centric view of small RNA regulation in bacteria [PDF]
Nature Reviews Microbiology, 2016 International audienceMany bacterial regulatory small RNAs (sRNAs) have several mRNA targets, which places them at the centre of regulatory networks that help bacteria to adapt to environmental changes.
Nara Figueroa-Bossi, Lionello Bossi
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Competing Endogenous RNA Networks in the Epithelial to Mesenchymal Transition in Diffuse-Type of Gastric Cancer [PDF]
Cancers, 2020 The diffuse-type of gastric cancer is associated with epithelial to mesenchymal transition. Loss of E-cadherin expression is the hallmark of this process and is largely due to the upregulation of the transcription factors ZEB1/2, Snail, Slug, and Twist1 ...
Natalia Landeros +2 more
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Competing Endogenous RNAs (ceRNAs) in Colorectal Cancer: A Review
Expert Reviews in Molecular Medicine, 2022Abstract Colorectal cancer (CRC) is a common type of cancer and the second leading cause of cancer-related deaths worldwide. Competing endogenous RNAs (ceRNAs) that contain microRNA response elements (MREs) are involved in CRC progression. They can compete with microRNAs (miRNAs) via their MREs, which can combine non-coding and coding RNAs via ...
Mohammad Hossein Akhbari +2 more
openaire +2 more sources
Competing endogenous RNA regulation in hematologic malignancies
Clinica Chimica Acta, 2020The clinical application of cytogenetic analysis and molecular-targeted drugs has dramatically improved the prognosis for many patients with hematologic malignancy, especially for those with chronic myeloid leukemia (CML) and acute promyelocytic leukemia (APL).
Han, Xiao, Simin, Liang, Li, Wang
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Journal of Cellular Physiology, 2018
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide. Despite the substantial advancement in understanding the molecular mechanisms and management of BC, it remains the leading cause of cancer death in women.
Rasoul Abdollahzadeh +5 more
semanticscholar +1 more source
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide. Despite the substantial advancement in understanding the molecular mechanisms and management of BC, it remains the leading cause of cancer death in women.
Rasoul Abdollahzadeh +5 more
semanticscholar +1 more source
A new algorithm for predicting competing endogenous rnas
Proceedings 2012 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS), 2012Competing endogenous RNAs, or ceRNAs, are sets of RNAs including mRNAs that can regulate each other by competing for microRNAs binding. ceRNAs form another level of regulation across the transcriptome and thus expand the function of microRNAs. CeRNAs have been shown to play important roles in disease like cancer [1].
Mario Flores, Yufei Huang 0001
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A Method for Constructing an Integrative Network of Competing Endogenous RNAs
2021Since the new gene regulation involving competing endogenous RNA (ceRNA) interactions targeted by common microRNAs (miRNAs) was found, several computational methods have been proposed to derive ceRNA networks. However, most of the ceRNA networks are restricted to represent either miRNA-target RNA interactions or lncRNA-miRNA-mRNA interactions. From the
Seokwoo Lee +3 more
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Posttranscriptional Regulation of PTEN by Competing Endogenous RNAs
2015PTEN expression can be dysregulated in cancers via multiple mechanisms including genomic loss, epigenetic silencing, transcriptional repression, and posttranscriptional regulation by microRNAs. MicroRNAs are short, noncoding RNAs that regulate gene expression by binding to recognition sites on target transcripts.
Yvonne, Tay, Pier Paolo, Pandolfi
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Competing Endogenous RNAs in Hepatocellular Carcinoma—The Pinnacle of Rivalry
Seminars in Liver Disease, 2019AbstractThe role of noncoding transcripts in gene expression is nowadays acknowledged to keep various diseases at bay—despite being referred to as “junk” DNA several years ago. Believed to be at the heart of multiple regulatory pathways, microRNAs (miRNAs) are small noncoding RNAs (ncRNAs) involved in posttranscriptional gene regulation.
Abdelrahman Yousry, Afify +5 more
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